2,3-Difluorobenzyl bromide
2,3-Difluorobenzyl bromide (CAS: 113211-94-2), with a molecular weight of 207.02 g/mol and linear formula F₂C₆H₃CH₂Br, is a fluorinated aryl building block. It is primarily utilised in organic synthesis, particularly in the preparation of complex molecules. This compound serves as a valuable intermediate in the development of pharmaceuticals and other fine chemicals, contributing to the advancement of chemical research and development.
- IUPAC
- α-Bromo-2,3-difluorotoluene
- Synonyms
- α-Bromo-2,3-difluorotolueneF2C6H3CH2Br
Pharmaceutical Intermediate
2,3-Difluorobenzyl bromide is employed as a key building block in the synthesis of various pharmaceutical compounds. Its specific structure allows for the introduction of a difluorobenzyl moiety into target molecules.
Chemical Synthesis Reagent
This compound acts as a versatile reagent in organic chemistry for the introduction of the 2,3-difluorobenzyl group. It is frequently used in research and development for creating novel chemical entities.
Research and Development
Used in academic and industrial laboratories for exploring new synthetic pathways and developing advanced materials. Its application in the synthesis of chemokine antagonists highlights its importance in medicinal chemistry research.
| Molecular weight | 207.02 |
|---|---|
| Linear formula | F2C6H3CH2Br |
| Assay | 98% |
| Density | 1.628 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.528(lit.) |
| Application | 2,3-Difluorobenzyl bromide was used in the synthesis of chemokine antagonists1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluorobenzyl bromide used for?
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2,3-Difluorobenzyl bromide is used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and fine chemicals, including its use in the synthesis of chemokine antagonists.
What are the CAS number and chemical formula for 2,3-Difluorobenzyl bromide?
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The CAS number is 113211-94-2, and the linear chemical formula is F₂C₆H₃CH₂Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Difluorobenzyl bromide with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or for nutraceutical/food grade use.
How is 2,3-Difluorobenzyl bromide shipped and exported?
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2,3-Difluorobenzyl bromide is shipped and exported according to strict international regulations for hazardous materials, identified as UN 3265, Class 8, Packing Group II.
What are the primary safety hazards associated with 2,3-Difluorobenzyl bromide?
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2,3-Difluorobenzyl bromide is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment including gloves, goggles, face shield, and respiratory protection is essential during handling.
How can I request a sample or a quote for 2,3-Difluorobenzyl bromide?
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To request a sample or a quote, please contact our sales team via the website or direct inquiry, providing your specific requirements.
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