2,3-Difluorobenzonitrile
2,3-Difluorobenzonitrile (CAS: 21524-39-0) is a fluorinated organic compound with the molecular formula F2C6H3CN and a molecular weight of 139.10 g/mol. This chemical serves as a valuable building block in organic synthesis. It is utilised in the preparation of various complex organic molecules, including difluorophenyl-1,2,3,5-dithiadiazolyl and cyanophenoxazines, making it a key intermediate in the development of novel chemical entities.
- Synonyms
- F2C6H3CN
Synthesis of Heterocyclic Compounds
2,3-Difluorobenzonitrile is employed as a precursor in the synthesis of heterocyclic structures. It has been documented for its use in preparing difluorophenyl-1,2,3,5-dithiadiazolyl derivatives, contributing to the field of sulphur and nitrogen-containing heterocycles.
Preparation of Phenoxazines
This compound is a useful reagent in the preparation of cyanophenoxazines. Its reactivity allows for the incorporation of the difluorobenzonitrile moiety into more complex molecular frameworks.
Fluorinated Organic Building Block
As a member of the fluorinated building blocks category, 2,3-Difluorobenzonitrile offers a difluorinated phenyl ring with a nitrile functional group. This makes it suitable for introducing fluorine atoms into target molecules, a common strategy in medicinal chemistry and materials science.
| Molecular weight | 139.10 |
|---|---|
| Linear formula | F2C6H3CN |
| Assay | 98% |
| Density | 1.254 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4882(lit.) |
| Application | 2,3-Difluorobenzonitrile has been used in the preparation of difluorophenyl-1,2,3,5-dithiadiazolyl1 and cyanophenoxazines2. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 75 °C / 167 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluorobenzonitrile used for?
+
2,3-Difluorobenzonitrile is primarily used as a building block in organic synthesis, particularly for the preparation of difluorophenyl-1,2,3,5-dithiadiazolyl and cyanophenoxazines.
What are the CAS number and molecular formula for 2,3-Difluorobenzonitrile?
+
The CAS number for 2,3-Difluorobenzonitrile is 21524-39-0, and its linear formula is F2C6H3CN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,3-Difluorobenzonitrile with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2,3-Difluorobenzonitrile be handled safely?
+
2,3-Difluorobenzonitrile is classified with warning signal word and hazard statements including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is 2,3-Difluorobenzonitrile packed, shipped, and exported?
+
2,3-Difluorobenzonitrile is packed according to industry standards for hazardous materials and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of 2,3-Difluorobenzonitrile?
+
To request a quote or sample of 2,3-Difluorobenzonitrile, please contact the Tech Serve Solutions sales department through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis