2,3-Difluorobenzaldehyde
2,3-Difluorobenzaldehyde (CAS 2646-91-5) is a fluorinated aromatic aldehyde with the molecular formula F2C6H3CHO and a molecular weight of 142.10 g/mol. Supplied with a 98% assay, this compound serves as a valuable building block in organic synthesis. Its chemical structure lends itself to the preparation of more complex molecules, particularly within pharmaceutical and materials science research. Tech Serve Solutions offers this reagent for your advanced chemical synthesis needs.
- Synonyms
- F2C6H3CHO2,3-Difluorobenzenecarboxaldehyde

Synthesis of Aminophosphine Derivatives
2,3-Difluorobenzaldehyde is documented for its use in the synthesis of aminophosphine structures. This application highlights its role as a key intermediate in constructing complex organophosphorus compounds.
Fluorinated Organic Building Block
As a difluorinated aromatic aldehyde, this compound is a versatile building block for introducing fluorinated moieties into organic molecules. It is particularly useful in medicinal chemistry and materials science where fluorine incorporation can modify pharmacokinetic or physical properties.
Intermediate in Chemical Synthesis
The aldehyde functionality and the presence of fluorine atoms make 2,3-Difluorobenzaldehyde a reactive intermediate for various chemical transformations. It can participate in condensation, reduction, and oxidation reactions, among others, enabling the synthesis of diverse chemical entities.
| Molecular weight | 142.10 |
|---|---|
| Linear formula | F2C6H3CHO |
| Assay | 98% |
| Boiling point | 64-65 °C/17 mmHg(lit.) |
| Density | 1.301 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.499(lit.) |
| Application | 2,3-Difluorobenzaldehyde was used in the synthesis of aminophosphine1. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1989C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluorobenzaldehyde used for?
+
2,3-Difluorobenzaldehyde is used as a building block in organic synthesis, notably in the preparation of aminophosphine derivatives and other complex fluorinated organic molecules.
What are the CAS number and formula for 2,3-Difluorobenzaldehyde?
+
The CAS number for 2,3-Difluorobenzaldehyde is 2646-91-5 and its linear formula is F2C6H3CHO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,3-Difluorobenzaldehyde with a minimum assay of 98%. This is a technical grade product and is not represented as USP, BP, or EP.
How should 2,3-Difluorobenzaldehyde be handled safely?
+
2,3-Difluorobenzaldehyde is a flammable liquid and vapour (H226) and causes skin (H315), eye (H319), and respiratory tract irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, ensuring good ventilation. Avoid ignition sources.
Is 2,3-Difluorobenzaldehyde available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,3-Difluorobenzaldehyde, and can fulfil international orders.
How can I request a quote or sample for 2,3-Difluorobenzaldehyde?
+
To request a quote or a sample of 2,3-Difluorobenzaldehyde, please contact our sales department through the website or by phone. We will be happy to assist you.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis