2,3-Difluoroaniline
2,3-Difluoroaniline (CAS: 4519-40-8) is a fluorinated aromatic amine with the molecular formula C6H5F2N and a molecular weight of 129.11 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the development of complex molecules. Its primary utility lies in its role as an intermediate for creating diverse chemical structures. Tech Serve Solutions supplies 2,3-Difluoroaniline with an assay of 98%.
- Synonyms
- 2,3-Difluorobenzeneamine4519-40-8F2C6H3NH2
Synthesis of Pyrimidine Derivatives
2,3-Difluoroaniline is employed in the synthesis of ethyl 2-arylamino-4-trifluoromethylpyrimidine-5-carboxylate. This application highlights its utility in constructing heterocyclic compounds with potential pharmaceutical relevance.
Fluorinated Organic Building Block
As an aryl fluorinated building block, 2,3-Difluoroaniline is a key intermediate for introducing fluorinated phenylamine moieties into larger organic molecules. This is crucial for modifying the electronic and lipophilic properties of target compounds.
Chemical Synthesis Intermediate
Its structure makes 2,3-Difluoroaniline suitable for various coupling reactions and functional group transformations in multi-step organic syntheses. It is widely used in research and development settings for creating novel chemical entities.
| Molecular weight | 129.11 |
|---|---|
| Linear formula | F2C6H3NH2 |
| Assay | 98% |
| Density | 1.274 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.514(lit.) |
| Application | 2,3-Difluoroaniline was used in the synthesis of ethyl 2-arylamino-4-trifluoromethylpyrimidine-5-carboxylate1. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-27-28-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluoroaniline used for?
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2,3-Difluoroaniline is used as a building block in organic synthesis, particularly for the creation of fluorinated heterocyclic compounds such as pyrimidine derivatives.
What is the CAS number and chemical formula for 2,3-Difluoroaniline?
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The CAS number for 2,3-Difluoroaniline is 4519-40-8, and its linear formula is C6H5F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Difluoroaniline with a minimum assay of 98%. This product is supplied for laboratory and research use; TSS does not represent it as USP, BP, or EP grade.
How should 2,3-Difluoroaniline be handled safely?
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2,3-Difluoroaniline is a Warning substance associated with hazards including harm if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, as well as respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used. Handle in a well-ventilated area.
Is 2,3-Difluoroaniline a controlled substance?
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Based on the provided data, 2,3-Difluoroaniline is not indicated as a controlled substance.
How can I request a quote or sample for 2,3-Difluoroaniline?
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To request a quote or sample of 2,3-Difluoroaniline, please contact the Tech Serve Solutions sales team through our website or by phone.
Is 2,3-Difluoroaniline available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,3-Difluoroaniline.
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