2,3-Difluoro-4-(tributylstannyl)pyridine
2,3-Difluoro-4-(tributylstannyl)pyridine (CAS 1245816-05-0), with a molecular weight of 404.13 g/mol and empirical formula C17H29F2NSn, is an organometallic reagent. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its difluoropyridine core and tributylstannyl group enable the introduction of functionalised pyridine moieties into complex molecular architectures, finding utility in pharmaceutical research and materials science.
- Synonyms
- C17H29F2NSn

Organic Synthesis Intermediate
Used as a precursor in Stille coupling reactions to introduce the 2,3-difluoropyridin-4-yl group into various organic molecules. This is crucial for constructing complex heterocyclic compounds.
Pharmaceutical Research
Facilitates the synthesis of novel drug candidates containing the difluoropyridine scaffold, which is of interest in medicinal chemistry due to its electronic properties and metabolic stability.
Materials Science
Enables the development of new functional materials by incorporating the fluorinated pyridine unit, potentially influencing electronic or optical properties.
| Molecular weight | 404.13 |
|---|---|
| Empirical formula | C17H29F2NSn |
| Assay | 95% |
| Density | 1.233 g/mL at 25 °C |



Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H372Causes damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P314Get medical attention if you feel unwell
- P501Dispose of contents and container per local regulations
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2788 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 21-25-36/38-48/23/25-50/53 |
| Safety statements (S) | 36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluoro-4-(tributylstannyl)pyridine used for?
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2,3-Difluoro-4-(tributylstannyl)pyridine is primarily used as an intermediate in organic synthesis, particularly for Stille coupling reactions, and in pharmaceutical research and materials science for the construction of functionalised pyridine-containing molecules.
What are the CAS number and molecular formula for 2,3-Difluoro-4-(tributylstannyl)pyridine?
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The CAS number is 1245816-05-0 and the empirical formula is C17H29F2NSn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a purity of 95% (assay). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,3-Difluoro-4-(tributylstannyl)pyridine be handled safely?
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This compound is classified as Dangerous. It is toxic if swallowed and in contact with skin, causes skin irritation, causes serious eye irritation, and damages organs through prolonged or repeated exposure. It is also toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area, avoiding release to the environment. Refer to the Safety Data Sheet for full details.
How is this chemical packed, shipped, and exported?
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This chemical is packed and shipped according to international regulations for hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide.
How can I request a sample or a quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 2,3-Difluoro-4-(tributylstannyl)pyridine.
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