2,3-Difluoro-4-formylphenylboronic acid
2,3-Difluoro-4-formylphenylboronic acid (CAS: 480424-84-8) is a specialised organoboron compound with the molecular formula F₂C₆H₂(CHO)B(OH)₂ and a molecular weight of 185.92 g/mol. It features a phenylboronic acid core substituted with two fluorine atoms and a formyl group. This trifunctional molecule serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions and the construction of complex organic frameworks for materials science and pharmaceutical research.
- IUPAC
- 2,3-Difluoro-4-formylbenzeneboronic acid
- Synonyms
- F2C6H2(CHO)B(OH)22,3-Difluoro-4-formylbenzeneboronic acid
Organic Synthesis
Utilised as a key intermediate in Suzuki-Miyaura cross-coupling reactions to introduce difluoroformylphenyl moieties into target molecules. This enables the synthesis of advanced materials and pharmaceutical candidates.
Medicinal Chemistry
Serves as a valuable building block for the synthesis of novel drug candidates. The difluorinated phenyl ring and aldehyde functionality offer unique electronic and steric properties for medicinal chemistry applications.
Materials Science
Employed in the development of functional organic materials, such as liquid crystals or organic semiconductors, where its specific substitution pattern can influence electronic and optical properties.
| Molecular weight | 185.92 |
|---|---|
| Linear formula | F2C6H2(CHO)B(OH)2 |
| Melting point | >300 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Difluoro-4-formylphenylboronic acid used for?
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2,3-Difluoro-4-formylphenylboronic acid is primarily used as a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the construction of complex organic molecules in pharmaceutical and materials science research.
What is the CAS number and formula for 2,3-Difluoro-4-formylphenylboronic acid?
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The CAS number is 480424-84-8 and the linear formula is F₂C₆H₂(CHO)B(OH)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research or technical grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications. Purity details are available upon request.
What are the safety and handling precautions for this chemical?
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This chemical requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is 2,3-Difluoro-4-formylphenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals adhering to all relevant international regulations for hazardous materials, ensuring safe and compliant delivery worldwide.
How can I request a sample or quote for 2,3-Difluoro-4-formylphenylboronic acid?
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To request a sample or a quotation for 2,3-Difluoro-4-formylphenylboronic acid, please contact our sales department through the TSS website or by calling our customer service line.
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