(R)-(−)-4-Phenyl-2-oxazolidinone
(R)-(−)-4-Phenyl-2-oxazolidinone (CAS: 90319-52-1; Formula: C9H9NO2; MW: 163.17 g/mol) is a chiral auxiliary used in asymmetric synthesis. This white to off-white crystalline solid is an essential building block for the stereoselective preparation of complex organic molecules, particularly in the synthesis of amino acids and certain antibiotic classes.
Chiral Auxiliary in Asymmetric Synthesis
This oxazolidinone derivative serves as a crucial chiral auxiliary, enabling the stereocontrolled synthesis of valuable organic compounds. Its defined stereochemistry facilitates the creation of enantiomerically enriched products.
Synthesis of α-Amino Acids
It is employed in the preparation of stereochemically pure α-amino acids, which are fundamental components of peptides and proteins, and are vital in pharmaceutical research and development.
Preparation of β-Lactam Antibiotics
The compound finds application in the synthetic routes towards β-lactam antibiotics, a significant class of antibacterial agents known for their efficacy in treating bacterial infections.
| Molecular weight | 163.17 |
|---|---|
| Empirical formula | C9H9NO2 |
| Assay | 98% |
| Optical activity | [α]25/D −48°, c = 2 in chloroform |
| Application | Used for α-amino acid synthesis1 and the preparation of β-lactam antibiotics.2 |
| Melting point | 131-133 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-4-Phenyl-2-oxazolidinone used for?
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(R)-(−)-4-Phenyl-2-oxazolidinone is used as a chiral auxiliary in asymmetric synthesis, notably for the preparation of α-amino acids and β-lactam antibiotics.
What are the CAS number and formula for (R)-(−)-4-Phenyl-2-oxazolidinone?
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The CAS number is 90319-52-1 and the molecular formula is C9H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-4-Phenyl-2-oxazolidinone with an assay of 98%. This product is not supplied as USP, BP, or EP grade.
How should (R)-(−)-4-Phenyl-2-oxazolidinone be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection.
Is (R)-(−)-4-Phenyl-2-oxazolidinone a controlled substance?
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This compound is not listed as a controlled substance in the provided data.
How are Tech Serve Solutions products typically packed and shipped?
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Tech Serve Solutions provides fine chemicals, pharmaceutical intermediates, and laboratory reagents for research and industrial use, exporting globally. Specific packaging and shipping details are confirmed upon order.
How can I request a sample or quote for (R)-(−)-4-Phenyl-2-oxazolidinone?
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To request a sample or quote, please use the contact form on our website or contact our sales department directly.
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