(R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone
(R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS 66673-40-3, C5H9NO2) is a valuable chiral building block. With a molecular weight of 115.13 g/mol, this heterocyclic compound is primarily utilized in asymmetric synthesis and chemical synthesis. It plays a role as a precursor in the creation of complex molecules, notably serving as a building block in the synthesis of diphthamide. Tech Serve Solutions supplies this chemical with a guaranteed assay of 99%.
- IUPAC
- D-Pyroglutaminol
Synthesis of Diphthamide
(R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone is employed as a key building block in the chemical synthesis of diphthamide, a unique amino acid found in eukaryotes.
Chiral Building Block in Asymmetric Synthesis
This compound serves as a versatile chiral intermediate in asymmetric synthesis, enabling the creation of enantiomerically pure compounds for various applications.
Heterocyclic Compound Synthesis
It functions as a useful precursor in the construction of more complex heterocyclic structures due to its pyrrolidinone ring and functional groups.
| Molecular weight | 115.13 |
|---|---|
| Empirical formula | C5H9NO2 |
| Assay | 99% |
| Boiling point | 147-149 °C/0.06 mmHg(lit.) |
| Optical activity | [α]20/D −31°, c = 5 in ethanol |
| Application | Serves as a building block in the synthesis of diphthamide.1 |
| Melting point | 83-85 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone used for?
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This compound is primarily used as a building block in chemical synthesis, particularly in the asymmetric synthesis of molecules such as diphthamide.
What are the CAS number and chemical formula for (R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone?
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The CAS number is 66673-40-3 and the chemical formula is C5H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone with an assay of 99%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone be handled?
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Handle with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This product is classified as a Warning with hazards H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation.
How is this chemical shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone, adhering to international shipping and export regulations.
How can I request a quote or sample?
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To request a quote or sample of (R)-(−)-5-(Hydroxymethyl)-2-pyrrolidinone, please contact our sales team through the website or provide your inquiry details.
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