Fmoc-2-Nal-OH

CAS 112883-43-9C28H23NO4Chemical Synthesis

Fmoc-2-Nal-OH (CAS: 112883-43-9) is a protected unnatural amino acid derivative with the molecular formula C28H23NO4 and a molecular weight of 437.49 g/mol. This compound serves as a crucial building block in peptide synthesis, particularly for incorporating naphthylalanine residues. Its Fmoc protecting group facilitates controlled peptide chain elongation, making it valuable in chemical biology and synthetic chemistry research.

IUPAC: Fmoc-3-(2-naphthyl)-L-alanine

Email us

Fmoc-2-Nal-OH (C28H23NO4) — chemical structure, CAS 112883-43-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Alanine DerivativesChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Fmoc-2-Nal-OH is employed in solid-phase and solution-phase peptide synthesis to introduce the unnatural amino acid 2-naphthylalanine into peptide sequences. This modification can alter peptide structure, stability, and biological activity.

Chemical Biology Research

It is used to create peptides with unique physicochemical properties for probing biological systems. The naphthyl group can serve as a fluorescent probe or influence receptor binding interactions.

Chemical Synthesis

This compound functions as a versatile intermediate in the synthesis of complex organic molecules, particularly those requiring non-proteinogenic amino acid moieties.

Unnatural Amino Acid Derivatives

As a derivative of alanine, it belongs to a class of compounds used to expand the chemical repertoire beyond the 20 standard amino acids for novel biomaterial and drug discovery.

02 /Properties

Molecular weight	437.49
Empirical formula	C28H23NO4
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

112883-43-9

MDL number

MFCD00144886

Beilstein registry

7668973

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-2-Nal-OH used for?

Fmoc-2-Nal-OH is primarily used in peptide synthesis to incorporate the unnatural amino acid 2-naphthylalanine into peptide chains. It is also valuable in chemical biology and general chemical synthesis for creating molecules with specific structural or functional properties.

What are the CAS number and formula for Fmoc-2-Nal-OH?

The CAS number for Fmoc-2-Nal-OH is 112883-43-9, and its empirical formula is C28H23NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-2-Nal-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any pharmacopoeial grade.

How should Fmoc-2-Nal-OH be handled and stored?

Handle Fmoc-2-Nal-OH with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. Store the compound at 2-8°C.

Is Fmoc-2-Nal-OH a controlled substance?

The provided data does not indicate that Fmoc-2-Nal-OH is a controlled substance. Its WGK Germany classification is 3.

How is Fmoc-2-Nal-OH shipped and exported?

Tech Serve Solutions exports fine chemicals globally. Specific shipping and handling procedures for Fmoc-2-Nal-OH adhere to international regulations for chemical transport.