1-(2-Methoxyphenyl)piperazine hydrochloride
1-(2-Methoxyphenyl)piperazine hydrochloride (CAS 5464-78-8) is the hydrochloride salt of an ortho-methoxy arylpiperazine, with molecular formula C11H16N2O·HCl and a molar mass of 228.72 g/mol. Typically a crystalline solid (melting point 217-219 °C), it serves as a heterocyclic building block and pharmaceutical intermediate. The methoxyphenyl-piperazine scaffold is widely used in medicinal-chemistry and chemical-synthesis research. Tech Serve Solutions supplies it as a research-grade reagent for laboratory and process applications.
- Synonyms
- 1-(2-Methoxyphenyl)piperazine hydrochloride2-Methoxyphenylpiperazine hydrochloride1-(o-Methoxyphenyl)piperazine hydrochlorideo-Methoxyphenylpiperazine hydrochloride1-(2-Methoxyphenyl)piperazine HClCAS 5464-78-8
Pharmaceutical intermediate
The 2-methoxyphenylpiperazine motif is a recognised building block in pharmaceutical and medicinal-chemistry synthesis. It is incorporated into target molecules where an arylpiperazine fragment is required.
Heterocyclic building block
Supplied for chemical-synthesis studies, the compound provides a substituted piperazine ring for N-alkylation, N-acylation and related coupling reactions in the construction of more complex structures.
Medicinal-chemistry research
Arylpiperazines of this type are common scaffolds in receptor-ligand discovery programmes. The compound is used as a reference fragment and starting material in structure-activity studies.
Laboratory reagent and reference material
As a defined-purity reagent, it is suitable for analytical and method-development work and as a synthetic precursor in research laboratories.
| Molecular weight | 228.72 |
|---|---|
| Empirical formula | C11H16N2O · HCl |
| Assay | 97% |
| Application | 1-(2-Methoxyphenyl)piperazine hydrochloride may be used in chemical synthesis studies. |
| Melting point | 217-219 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Methoxyphenyl)piperazine hydrochloride used for?
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It is used mainly as a heterocyclic building block and pharmaceutical intermediate in chemical synthesis. The 2-methoxyphenylpiperazine scaffold is a common fragment in medicinal-chemistry and receptor-ligand research, where it is functionalised to build more complex target molecules.
What is the CAS number and molecular formula of 1-(2-Methoxyphenyl)piperazine hydrochloride?
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The CAS number is 5464-78-8 and the molecular formula is C11H16N2O·HCl, corresponding to a molecular weight of 228.72 g/mol. The MDL number is MFCD00012762 and the EC number is 226-762-6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a typical assay of 97%, as a research/technical-grade reagent. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch.
What are the safety and handling requirements?
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Classified under GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and work with adequate ventilation. WGK (Germany) water-hazard class is 3, so prevent release to drains and waterways.
How is 1-(2-Methoxyphenyl)piperazine hydrochloride packed, shipped and exported?
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It is packed in sealed, appropriately labelled containers sized from research quantities to bulk, with full GHS labelling and documentation. As a global supplier and exporter, Tech Serve Solutions arranges compliant international shipment with a certificate of analysis and safety data sheet; pack sizes can be tailored to requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, documentation and a quotation. Samples can be arranged for qualification, subject to standard order terms.
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