1-(2-Methylpropyl)-4-piperidone
1-(2-Methylpropyl)-4-piperidone (CAS 72544-16-2) is an N-isobutyl-substituted 4-piperidone with the molecular formula C9H17NO and a molar mass of 155.24 g/mol. It is a liquid heterocyclic building block (refractive index n20/D 1.456; density 0.914 g/mL at 25 degrees C) supplied at 97% assay. The reactive 4-keto group and tertiary amine make it a versatile intermediate for chemical synthesis and the preparation of functionalised piperidine derivatives.
- Synonyms
- 1-(2-Methylpropyl)-4-piperidone1-Isobutyl-4-piperidone1-Isobutylpiperidin-4-oneN-Isobutyl-4-piperidone1-(2-Methylpropyl)piperidin-4-one1-(2-Methylpropyl)-4-piperidinone
Heterocyclic building block
Serves as an N-alkylated 4-piperidone scaffold in chemical synthesis, providing a piperidine ring already bearing an isobutyl group on nitrogen and a ketone at the 4-position.
Intermediate for piperidine derivatives
The 4-keto function undergoes reductive amination, condensation and addition reactions, allowing conversion to 4-substituted and 4-amino piperidines used in onward synthesis.
Pharmaceutical and fine-chemical research
Used as a research-grade intermediate in medicinal-chemistry and fine-chemical programmes where a pre-functionalised piperidone core is required for further elaboration.
Laboratory reagent
Applied in research and method-development work as a defined small-molecule reagent for exploratory and structure-activity studies.
| Molecular weight | 155.24 |
|---|---|
| Empirical formula | C9H17NO |
| Assay | 97% |
| Boiling point | 220 °C(lit.) |
| Density | 0.914 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.456(lit.) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Methylpropyl)-4-piperidone used for?
+
It is used mainly as a heterocyclic building block and synthetic intermediate. The combination of an isobutyl-substituted piperidine nitrogen and a reactive 4-ketone makes it useful for preparing functionalised piperidine derivatives in pharmaceutical and fine-chemical research.
What is the CAS number and molecular formula of 1-(2-Methylpropyl)-4-piperidone?
+
The CAS number is 72544-16-2 and the molecular formula is C9H17NO, with a molecular weight of 155.24 g/mol. Related identifiers include MDL number MFCD00190595, EC number 276-712-2 and PubChem substance ID 24879310.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-(2-Methylpropyl)-4-piperidone as a research/technical grade at a typical assay of 97%. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
How should 1-(2-Methylpropyl)-4-piperidone be handled and stored?
+
Handle it with appropriate laboratory controls, using eye protection, gloves and suitable respiratory protection where vapours or aerosols may form, in a well-ventilated area. It is a combustible liquid with a flash point of about 93 degrees C and is classified WGK 3 (severely hazardous to water in Germany), so keep it away from drains and water courses. Recommended storage is 2-8 degrees C; always consult the current Safety Data Sheet before use.
How is 1-(2-Methylpropyl)-4-piperidone packed, shipped and exported?
+
It is packed in suitably sealed, compatible containers sized to the order and labelled in line with applicable regulations, with batch documentation included. As a global supplier and exporter, Tech Serve Solutions arranges cold-chain-aware, compliant shipping and the required export paperwork for international destinations.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, and we will respond with availability, lead time, packing options and a formal quotation. Samples can be arranged where appropriate for evaluation.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis