1-(2-Phenylethyl)piperazine
1-(2-Phenylethyl)piperazine is an organic building block with CAS number 5321-49-3, molecular formula C12H18N2 and a molar mass of 190.28 g/mol. Also called 1-phenethylpiperazine, it is a mono-substituted piperazine bearing a 2-phenylethyl group on one ring nitrogen, leaving a reactive secondary amine. Tech Serve Solutions supplies it at 97% assay as a research and synthesis-grade reagent for pharmaceutical-intermediate and fine-chemical chemistry. It is corrosive and toxic if swallowed.
- IUPAC
- 1-Phenethylpiperazine
- Synonyms
- 1-(2-Phenylethyl)piperazine1-Phenethylpiperazine1-(2-phenethyl)piperazine1-(2-Phenylethyl)-piperazineN-(2-Phenylethyl)piperazine2-Phenylethylpiperazine
Pharmaceutical-intermediate synthesis
Used as a heterocyclic building block in the preparation of pharmaceutical intermediates and active-ingredient candidates. The free secondary amine offers a convenient handle for acylation, alkylation and reductive amination.
Piperazine scaffold chemistry
Serves as a substituted piperazine core in medicinal-chemistry and discovery programmes, where the piperazine ring is a frequently used motif for tuning solubility and basicity.
Fine-chemical and custom synthesis
Employed as a C12 intermediate in multi-step routes to specialty and fine chemicals. It readily forms salts and amide or sulfonamide derivatives for downstream coupling steps.
Laboratory reagent and reference material
Supplied as a research-grade reagent for method development, analytical work and exploratory synthesis where a defined 97% assay material is required.
| Molecular weight | 190.28 |
|---|---|
| Empirical formula | C12H18N2 |
| Assay | 97% |
| Boiling point | 276 °C(lit.) |
| Density | >1.006 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.5430(lit.) |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2922 8/PG 3 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C,Xn |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Phenylethyl)piperazine used for?
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It is used principally as a building block and intermediate in chemical synthesis, particularly for pharmaceutical intermediates and other fine chemicals. Its reactive secondary amine makes it useful for acylation, alkylation and reductive-amination steps that build more complex piperazine-containing molecules.
What is the CAS number and molecular formula of 1-(2-Phenylethyl)piperazine?
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The CAS number is 5321-49-3 and the molecular formula is C12H18N2, corresponding to a molecular weight of 190.28 g/mol. Its EC number is 226-186-5 and the MDL number is MFCD00040740.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(2-Phenylethyl)piperazine at a typical assay of 97% as a technical/research-grade reagent for synthesis and laboratory use. We do not represent this material as USP, BP or EP pharmacopoeia grade. A certificate of analysis is provided with each batch.
What are the safety and handling precautions for 1-(2-Phenylethyl)piperazine?
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It is classified under GHS with the signal word Danger and pictograms GHS05 and GHS06. The hazard statements are H301 (toxic if swallowed) and H314 (causes severe skin burns and eye damage). Handle with gloves, goggles or face shield and suitable respiratory protection, avoid all contact, and consult the SDS before use.
How is 1-(2-Phenylethyl)piperazine packed, shipped and exported?
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It is packed in appropriately labelled containers sized to the order and shipped with full documentation, including a certificate of analysis and safety data sheet. For transport it is classified as UN 2922, Class 8, Packing Group III, and is handled in line with applicable dangerous-goods regulations for export.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and delivery destination, and our team will confirm availability, lead time and documentation. We can arrange samples and bulk quotations for laboratory, pilot and commercial volumes.
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