1-(2-Pyridyl)piperazine
1-(2-Pyridyl)piperazine (CAS 34803-66-2) is a heterocyclic organic building block with the molecular formula C9H13N3 and a molar mass of 163.22 g/mol. Combining a piperazine ring with a 2-pyridyl substituent, it is supplied as a high-purity liquid reagent (assay ≥99%). It serves principally as a synthetic intermediate in medicinal and fine-chemical chemistry and as a derivatising reagent for the determination of aliphatic and aromatic isocyanates in air.
- IUPAC
- 2-Piperazinopyridine
- Synonyms
- 1-(2-Pyridyl)piperazine2-Piperazinopyridine1-(Pyridin-2-yl)piperazine1-(2-Pyridinyl)piperazine2-(1-Piperazinyl)pyridine
Isocyanate air monitoring reagent
1-(2-Pyridyl)piperazine is a well-established derivatising agent used to sample and determine aliphatic and aromatic isocyanates in workplace air. Its secondary amine reacts with isocyanate groups to form stable ureas suitable for chromatographic quantification.
Heterocyclic building block
As a piperazine bearing a 2-pyridyl group, it is a versatile scaffold in chemical synthesis. The free N-H of the piperazine ring offers a reactive handle for alkylation, acylation and coupling reactions.
Pharmaceutical and fine-chemical intermediate
The pyridylpiperazine motif is common in medicinal chemistry, making this compound a useful intermediate for the preparation of more complex target molecules. It is supplied for research and manufacturing use.
Laboratory reagent
Supplied at ≥99% assay, it is suitable for analytical and preparative laboratory work where a defined, high-purity pyridylpiperazine is required.
| Molecular weight | 163.22 |
|---|---|
| Empirical formula | C9H13N3 |
| Assay | ≥99% |
| Boiling point | 120-122 °C/2 mmHg(lit.) |
| Density | 1.072 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.595(lit.) |
| Application | 1-(2-Pyridyl)piperazine was used to determine the aliphatic and aromatic isocyanates in air1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Pyridyl)piperazine used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate in medicinal and fine-chemical chemistry, and as a derivatising reagent for determining aliphatic and aromatic isocyanates in air. The reactive piperazine N-H allows further functionalisation in synthesis.
What is the CAS number and molecular formula of 1-(2-Pyridyl)piperazine?
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The CAS number is 34803-66-2 and the molecular formula is C9H13N3, corresponding to a molecular weight of 163.22 g/mol. It is also identified by EC number 252-220-3 and MDL number MFCD00006216.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(2-Pyridyl)piperazine at an assay of ≥99% as a research and technical-grade reagent. We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch.
What are the safety and handling requirements for 1-(2-Pyridyl)piperazine?
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It carries GHS pictogram GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Use eye protection, gloves and suitable respiratory protection, handle with adequate ventilation, and consult the SDS before use. It is classified WGK 3 (highly hazardous to water), so prevent release to the environment.
How is 1-(2-Pyridyl)piperazine packed, shipped and exported?
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It is packed in appropriately sealed containers sized to the order, labelled in line with GHS requirements and accompanied by an SDS and certificate of analysis. As a global supplier and exporter, Tech Serve Solutions arranges compliant documentation and shipping to international destinations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and delivery destination, and our team will respond with availability, lead time and a quotation. Samples can be arranged on request, subject to availability.
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