1-(2-Pyrrolecarbonyl)benzotriazole
1-(2-Pyrrolecarbonyl)benzotriazole (CAS 144223-32-5; C11H8N4O; molar mass 212.21 g/mol) is an N-acylbenzotriazole reagent that serves as a bench-stable, isolable equivalent of an activated pyrrole-2-carbonyl donor. As a benzotriazole-mediated acylating agent it transfers the pyrrole-2-carbonyl group to amines, alcohols, thiols and carbon nucleophiles under mild conditions. Tech Serve Solutions supplies it at 97% assay as a research-grade synthetic reagent for laboratory and process chemistry.
- IUPAC
- 1-(1H-Pyrrol-2-ylcarbonyl)-1H-benzotriazole
- Synonyms
- 1-(2-Pyrrolecarbonyl)benzotriazole1-(1H-Pyrrol-2-ylcarbonyl)-1H-benzotriazole2-(1H-Benzotriazol-1-ylcarbonyl)-1H-pyrroleN-(2-Pyrrolylcarbonyl)benzotriazolePyrrole-2-carbonyl benzotriazole
Acylating reagent for amide formation
Acts as a stable, easily handled acyl donor that converts amines into the corresponding pyrrole-2-carboxamides under mild conditions, with benzotriazole released as a readily removed leaving group.
C-C bond formation
Used in benzotriazole-mediated carbon-carbon bond-forming reactions to introduce the pyrrole-2-carbonyl moiety onto suitable carbon nucleophiles, supporting the synthesis of pyrrole-containing ketones and related structures.
Ester and thioester synthesis
Reacts with alcohols and thiols to deliver pyrrole-2-carboxylic esters and thioesters, offering a controllable alternative to acid chlorides and coupling-reagent methods.
Building block for heterocyclic chemistry
Provides a convenient route to install the pyrrole-2-carbonyl group when assembling more complex heterocyclic and pharmaceutical-intermediate scaffolds in research synthesis.
Synthetic reagent for medicinal-chemistry research
Applied in discovery-stage and process chemistry where a mild, selective acyl-transfer reagent is preferred for late-stage functionalisation of sensitive substrates.
| Molecular weight | 212.21 |
|---|---|
| Empirical formula | C11H8N4O |
| Assay | 97% |
| Melting point | 178-182 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Pyrrolecarbonyl)benzotriazole used for?
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It is used as a benzotriazole-activated acylating reagent that transfers the pyrrole-2-carbonyl group to amines, alcohols, thiols and carbon nucleophiles. This makes it a convenient, bench-stable tool for preparing pyrrole-2-carboxamides, esters, thioesters and related compounds, and for carbon-carbon bond formation in synthetic chemistry.
What is the CAS number and molecular formula of 1-(2-Pyrrolecarbonyl)benzotriazole?
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The CAS number is 144223-32-5 and the molecular formula is C11H8N4O, with a molecular weight of 212.21 g/mol. The MDL number is MFCD00962972, and a common synonym is 1-(1H-Pyrrol-2-ylcarbonyl)-1H-benzotriazole.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(2-Pyrrolecarbonyl)benzotriazole at a typical assay of 97% as a research-grade synthetic reagent. We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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The product is classified under GHS07 with the signal word Warning and hazard statement H302 (harmful if swallowed). Avoid ingestion, dust formation and contact with skin and eyes; handle with a type N95 dust mask, eye protection and gloves in a well-ventilated area. It carries the German water-hazard class WGK 3, so prevent release to drains and watercourses. Always consult the Safety Data Sheet before use.
How is 1-(2-Pyrrolecarbonyl)benzotriazole packed, shipped and exported?
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It is supplied as a solid in tightly sealed containers sized to the order, with full labelling and a Safety Data Sheet. Tech Serve Solutions exports worldwide with appropriate export documentation and shipping arrangements suited to laboratory and bulk research quantities.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packing preference and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged where appropriate for evaluation.
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