Tetramethylrhodamine-5-maleimide
Tetramethylrhodamine-5-maleimide (CAS: 174568-67-3) is a fluorescent labelling reagent with the molecular formula C28H23N3O5 and a molecular weight of 481.50 g/mol. This rhodamine derivative is suitable for fluorescence applications, particularly for labelling sulfhydryl groups in proteins and other biomolecules. Its specific excitation and emission wavelengths make it valuable in biochemical research for protein modification and structural analysis.
Fluorescent Labeling of Biomolecules
Tetramethylrhodamine-5-maleimide reacts with sulfhydryl groups to covalently attach a fluorescent tag. This is commonly used for labelling proteins, peptides, and antibodies for detection and quantification in various biological assays.
Protein Modification and Analysis
This reagent facilitates the study of protein structure and function by allowing for fluorescent tracking. It is applicable in proteomics and protein structural analysis techniques.
Biochemical Research
As a biochemical reagent, it finds use in diverse research settings investigating cellular processes, molecular interactions, and the development of fluorescent probes.
| Molecular weight | 481.50 |
|---|---|
| Empirical formula | C28H23N3O5 |
| Assay | ≥85% (HPLC) |
| Solubility | DMSO: solublemethanol: soluble |
| Storage temperature | −20°C |
| Suitability | suitable for fluorescence |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 543 nm; λem 575 nm in 0.1 M phosphate pH 7.0 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylrhodamine-5-maleimide used for?
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Tetramethylrhodamine-5-maleimide is primarily used as a fluorescent labelling reagent for sulfhydryl groups on biomolecules, such as proteins and peptides. It is valuable for protein modification, structural analysis, and in general biochemical and molecular biology research.
What are the CAS number and formula for Tetramethylrhodamine-5-maleimide?
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The CAS number for Tetramethylrhodamine-5-maleimide is 174568-67-3, and its empirical formula (Hill notation) is C28H23N3O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylrhodamine-5-maleimide with an assay of ≥85% (HPLC). This product is suitable for fluorescence applications and is intended for research use. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Tetramethylrhodamine-5-maleimide be handled safely?
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Handling Tetramethylrhodamine-5-maleimide requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The product carries a WGK Germany rating of 3, indicating it is hazardous.
What are the storage conditions for Tetramethylrhodamine-5-maleimide?
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Tetramethylrhodamine-5-maleimide should be stored at -20°C to maintain its stability and efficacy.
How can I request a quote or sample for Tetramethylrhodamine-5-maleimide?
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To request a quote or a sample of Tetramethylrhodamine-5-maleimide, please contact the TSS sales team through our website or by phone. We are a global supplier and exporter of fine chemicals.
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