Tetramisole hydrochloride
Tetramisole hydrochloride (CAS: 5086-74-8), with the molecular formula C11H12N2S · HCl and a molecular weight of 240.75 g/mol, is a potent inhibitor of various mammalian alkaline phosphatases. It is particularly effective against enzymes found in the liver, kidney, placenta, bone, and tumors, with minimal inhibition of intestinal alkaline phosphatases. This compound serves as a valuable tool in biochemical research and enzymatic studies.
- IUPAC
- (±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
Mammalian Alkaline Phosphatase Inhibition
Tetramisole hydrochloride is primarily used to inhibit various mammalian alkaline phosphatases, including those present in the liver, kidney, placenta, bone, and tumor tissues. This makes it a useful reagent for researchers studying enzyme kinetics and function.
Biochemical Research
As an enzyme inhibitor, tetramisole hydrochloride is employed in biochemical research to modulate the activity of alkaline phosphatases. Its specific inhibitory action aids in understanding cellular processes and enzyme mechanisms.
Enzymology Studies
This compound is instrumental in enzyme studies, allowing scientists to investigate the role of alkaline phosphatases in biological systems by selectively blocking their activity. It is noted for having only slight inhibitory effects on intestinal alkaline phosphatases.
| Molecular weight | 240.75 |
|---|---|
| Empirical formula | C11H12N2S · HCl |
| Application | Suitable for inhibition of various mammalian alkaline phosphatases (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited. |
| Melting point | 266-267 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | alkaline phosphatase inhibitor |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramisole hydrochloride used for?
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Tetramisole hydrochloride is used for the inhibition of various mammalian alkaline phosphatases, particularly those found in the liver, kidney, placenta, bone, and tumors. It is also utilised in biochemical and enzymology research.
What is the CAS number and formula for Tetramisole hydrochloride?
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The CAS number for Tetramisole hydrochloride is 5086-74-8, and its molecular formula is C11H12N2S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramisole hydrochloride as a research-grade chemical. While the exact assay is not specified here, TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Tetramisole hydrochloride?
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Tetramisole hydrochloride is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, should be worn. Handle in a well-ventilated area.
How is Tetramisole hydrochloride packed, shipped, and exported?
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Tetramisole hydrochloride is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions, adhering to all necessary regulations for chemical shipments.
How can I request a sample or quote for Tetramisole hydrochloride?
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To request a sample or a quotation for Tetramisole hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone. Please include the product name and CAS number in your request.
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