Tetramethylrhodamine methyl ester perchlorate
Tetramethylrhodamine methyl ester perchlorate (CAS: 115532-50-8) is a vital fluorescent probe with the chemical formula C25H25N2O3 · ClO4. Possessing a molecular weight of 500.93 g/mol, this compound is recognised for its sensitive detection of mitochondrial membrane potential. It is extensively utilised in cell biology research for understanding cellular function and viability. Tech Serve Solutions supplies this reagent with a purity of ≥95%, ensuring reliable experimental outcomes.
- IUPAC
- TMRM
Mitochondrial Membrane Potential Probe
Tetramethylrhodamine methyl ester perchlorate is a lipophilic cationic dye that accumulates in active mitochondria. Its fluorescence intensity correlates with the negative potential across the inner mitochondrial membrane, making it a sensitive indicator of cellular energy status and function.
Cell Viability and Apoptosis Assays
By monitoring changes in mitochondrial membrane potential, TMRM can be used to assess cell viability and detect early signs of apoptosis. A decrease in mitochondrial membrane potential is a hallmark of programmed cell death.
Fluorescent Labeling in Cell Biology
This compound serves as a valuable fluorescent tool in various cell biology applications, aiding researchers in visualising and quantifying mitochondrial activity and integrity within living cells.
| Molecular weight | 500.93 |
|---|---|
| Linear formula | C25H25N2O3 · ClO4 |
| Assay | ≥95% |
| Storage temperature | 2-8°C |
| Application | Sensitive probe for mitochondrial membrane potential. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λem 573 nm in methanol |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylrhodamine methyl ester perchlorate used for?
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Tetramethylrhodamine methyl ester perchlorate is primarily used as a sensitive fluorescent probe for evaluating mitochondrial membrane potential in cell biology research, aiding in the assessment of cellular viability and function.
What are the CAS number and formula for Tetramethylrhodamine methyl ester perchlorate?
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The CAS number for Tetramethylrhodamine methyl ester perchlorate is 115532-50-8, and its chemical formula is C25H25N2O3 · ClO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylrhodamine methyl ester perchlorate with a minimum purity of 95% (≥95%). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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Tetramethylrhodamine methyl ester perchlorate is classified with a Warning signal word, indicating hazards such as skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn during handling. Ensure good ventilation and avoid breathing dust.
How is Tetramethylrhodamine methyl ester perchlorate packed, shipped, and exported?
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Tech Serve Solutions carefully packs and prepares chemicals for shipment, adhering to international regulations for the export of laboratory reagents and fine chemicals. Specific packaging details ensure product integrity and compliance during transit.
How can I request a sample or quote for Tetramethylrhodamine methyl ester perchlorate?
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To request a sample or a quotation for Tetramethylrhodamine methyl ester perchlorate, please visit the Tech Serve Solutions website or contact our sales department directly. Our team will be pleased to assist you with your requirements.
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