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Tetramethylrhodamine isothiocyanate mixed isomers

CAS 95197-95-8C25H21N3O3SBiochemicals & Reagents

Tetramethylrhodamine isothiocyanate (MRITC), mixed isomers (CAS: 95197-95-8), is a fluorescent labeling reagent with the empirical formula C25H21N3O3S. It is valued for its fluorescence properties, with an excitation maximum of 529 nm and emission maximum of 596 nm in DMSO. This compound is soluble in DMSO and methanol, making it a versatile tool for various biochemical and analytical applications requiring fluorescent detection.

IUPAC
MRITC,TRITC,Tetramethylrhodamine B isothiocyanate
Synonyms
MRITCTRITCTetramethylrhodamine B isothiocyanate
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Tetramethylrhodamine isothiocyanate mixed isomers (C25H21N3O3S) — chemical structure, CAS 95197-95-8; Life Science, fine chemical supplied by Tech Serve Solutions
Analytical ReagentsAnalytical/ChromatographyBiochemicals and ReagentsDerivatization ReagentsDerivatization Reagents HPLCDetectionFluorescenceFluorescent LabelsFluorescent ProbesLabels
01 /Applications

Fluorescent Labeling

Tetramethylrhodamine isothiocyanate serves as a fluorescent label for biomolecules, enabling their visualization and tracking in various biological assays. Its reactive isothiocyanate group allows for covalent conjugation to amine groups present in proteins and other macromolecules.

Biochemical Assays

This reagent is utilised in a range of biochemical studies and assays where fluorescent detection is required. It can be employed in microscopy, flow cytometry, and other analytical techniques to detect and quantify specific biological targets.

Derivatization Reagent

MRITC can be used as a derivatization reagent, particularly in High-Performance Liquid Chromatography (HPLC), to enhance the detectability of analytes. Its fluorescent properties aid in sensitive detection of substances that may otherwise be difficult to quantify.

02 /Properties
Empirical formulaC25H21N3O3S
SolubilityDMSO: solublemethanol: soluble
Storage temperature2-8°C
Suitabilitysuitable for fluorescence
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H315Causes skin irritation
  • H317May cause an allergic skin reaction
  • H319Causes serious eye irritation
  • H334May cause allergy or asthma symptoms if inhaled
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P342
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)36/37/38-42
Safety statements (S)22-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
95197-95-8
05 /Additional specifications
Fluorescenceλex 529 nm; λem 596 nm in DMSO
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Tetramethylrhodamine isothiocyanate (mixed isomers) used for?

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Tetramethylrhodamine isothiocyanate (mixed isomers) is primarily used as a fluorescent labeling reagent for biomolecules and in various biochemical assays and derivatization techniques, particularly for HPLC, due to its fluorescence properties (λex 529 nm; λem 596 nm in DMSO).

What is the CAS number and formula for Tetramethylrhodamine isothiocyanate (mixed isomers)?

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The CAS number for Tetramethylrhodamine isothiocyanate (mixed isomers) is 95197-95-8, and its empirical formula is C25H21N3O3S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Tetramethylrhodamine isothiocyanate (mixed isomers) as a research grade chemical. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Tetramethylrhodamine isothiocyanate (mixed isomers) be handled safely?

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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves. Avoid inhalation of dust and contact with skin and eyes, as it may cause skin irritation, eye irritation, and respiratory irritation.

How is Tetramethylrhodamine isothiocyanate (mixed isomers) packed and shipped?

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Tetramethylrhodamine isothiocyanate (mixed isomers) is typically stored at 2-8°C. Tech Serve Solutions exports this chemical globally, adhering to all relevant shipping regulations for chemical compounds.

How can I request a sample or quote for Tetramethylrhodamine isothiocyanate (mixed isomers)?

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To request a sample or a quote for Tetramethylrhodamine isothiocyanate (mixed isomers), please contact the Tech Serve Solutions sales department via our website or by phone.

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