Tetrahydrozoline hydrochloride
Tetrahydrozoline hydrochloride (CAS 522-48-5, C13H16N2 · HCl) is a sympathomimetic amine with a molecular weight of 236.74 g/mol. This compound acts as an alpha-adrenergic agonist, primarily recognised for its vasoconstrictive properties. It is a key ingredient in various over-the-counter ophthalmic solutions for temporary relief of redness due to minor eye irritations. Tetrahydrozoline hydrochloride is also used in nasal decongestants.
- IUPAC
- 4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole monohydrochloride,Tetryzoline hydrochloride
- Synonyms
- Tetryzoline hydrochloride4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole monohydrochloride
Ophthalmic Solutions
Utilised for its vasoconstrictive action in eye drops to temporarily relieve redness caused by minor irritations. It constricts blood vessels in the eye, reducing swelling and discomfort.
Nasal Decongestants
Incorporated into some nasal spray formulations to alleviate nasal congestion. Its vasoconstrictive effects help to reduce swelling of the nasal mucosa.
Research Chemical
Serves as a research tool for studies investigating adrenergic receptor activity and related physiological mechanisms. Its well-defined pharmacological profile makes it valuable in preclinical research.
| Molecular weight | 236.74 |
|---|---|
| Empirical formula | C13H16N2 · HCl |
| Assay | ≥98% |
| Solubility | H2O: freely solublealcohol: freely solublechloroform: very slightly solublediethyl ether: insoluble |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrahydrozoline hydrochloride used for?
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Tetrahydrozoline hydrochloride is primarily used in ophthalmic solutions to relieve minor eye redness and in nasal sprays as a decongestant due to its vasoconstrictive properties.
What is the CAS number and molecular formula?
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The CAS number for Tetrahydrozoline hydrochloride is 522-48-5, and its molecular formula is C13H16N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrahydrozoline hydrochloride with an assay of ≥98%. This product is supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
How should Tetrahydrozoline hydrochloride be handled safely?
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Handle with care. Tetrahydrozoline hydrochloride (CAS 522-48-5) is harmful if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Use appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves.
Is Tetrahydrozoline hydrochloride a controlled substance?
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The provided data does not indicate that Tetrahydrozoline hydrochloride is a controlled substance.
How is Tetrahydrozoline hydrochloride packed and shipped?
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Tetrahydrozoline hydrochloride is packed according to industry best practices for chemical reagents and exported globally by Tech Serve Solutions.
How can I request a sample or quote for Tetrahydrozoline hydrochloride?
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To request a sample or a quote for Tetrahydrozoline hydrochloride, please contact our sales department through our website or by phone.
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