Tetrahydrofolic acid

CAS 135-16-0C19H23N7O6Biochemicals & Reagents

Tetrahydrofolic acid (CAS: 135-16-0; C19H23N7O6; MW: 445.43) is a vital biological cofactor essential for numerous metabolic processes, including amino acid and nucleotide synthesis. This faintly yellow to light brown powder serves as a critical intermediate in folate metabolism. Its primary research application involves studying the activation of riboswitches, a key mechanism in gene regulation. Tech Serve Solutions supplies this compound for laboratory and research purposes.

IUPAC: 5,6,7,8-Tetrahydropteroyl-L-glutamic acid,THF
Synonyms: 5,6,7,8-Tetrahydropteroyl-L-glutamic acid,THF

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Tetrahydrofolic acid (C19H23N7O6) — chemical structure, CAS 135-16-0; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsCell BiologyCofactorCofactorsEnzymesInhibitorsand SubstratesFolicFolic Acid MetabolismMetabolic Pathways

01 /Applications

RiboSwitch Activation Studies

Tetrahydrofolic acid (THF) is utilised in research to investigate the activation mechanisms of riboswitches. This helps scientists understand gene regulation processes at a molecular level.

Cofactor in Metabolic Research

As a fundamental cofactor, THF plays a role in various metabolic pathways. It is employed in studies examining nucleotide and amino acid biosynthesis, crucial for cellular function.

Biochemical Research

This compound is a valuable reagent in biochemical research, contributing to a deeper understanding of cellular processes and metabolic pathways within biological systems.

02 /Properties

Molecular weight	445.43
Empirical formula	C19H23N7O6
Assay	≥65% (when packaged)
Form	powder
Colour	faintly yellow to light brown
Storage temperature	−20°C
Application	A recent use of tetrahydrofolate (THF) is for the studying the activation of riboswitches.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

135-16-0

MDL number

MFCD00135583

PubChem substance

24900106

Beilstein registry

9238187

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tetrahydrofolic acid used for?

Tetrahydrofolic acid (THF) is primarily used in research to study the activation of riboswitches and as a cofactor in various metabolic pathways, including amino acid and nucleotide synthesis.

What is the CAS number and formula for Tetrahydrofolic acid?

The CAS number for Tetrahydrofolic acid is 135-16-0, and its empirical formula (Hill notation) is C19H23N7O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tetrahydrofolic acid with an assay of ≥65% (when packaged). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Tetrahydrofolic acid be handled and stored?

Handling Tetrahydrofolic acid requires personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It should be stored at -20°C.

How is Tetrahydrofolic acid supplied and exported?

Tetrahydrofolic acid is supplied as a powder and is available for global export by Tech Serve Solutions, adhering to all necessary regulations.

How can I request a sample or quote for Tetrahydrofolic acid?

To request a sample or quote for Tetrahydrofolic acid, please contact our sales team via the website or direct email, referencing the product name and CAS number (135-16-0).