Tetraisopropyl pyrophosphoramide
Tetraisopropyl pyrophosphoramide (CAS 513-00-8), with the molecular formula C12H32N4O3P2 and a molecular weight of 342.36 g/mol, is a chemical compound primarily utilised as a potent inhibitor of cholinesterase enzymes. It is recognised for its role in biochemical research, particularly in studies involving enzyme kinetics and cellular processes regulated by acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). This compound serves as a valuable tool for researchers investigating enzyme function and developing therapeutic strategies.
- IUPAC
- Tetra(monoisopropyl)pyrophosphortetramide,iso-OMPA
- Synonyms
- iso-OMPATetra(monoisopropyl)pyrophosphortetramide

Enzyme Inhibition Studies
Tetraisopropyl pyrophosphoramide acts as a strong inhibitor of both human acetylcholinesterase (ACHE) and butyrylcholinesterase (BCHE). It is used in biochemical and cell biology research to study enzyme mechanisms, kinetics, and the physiological roles of these critical enzymes.
Biochemical Research Reagent
As a bioactive small molecule, this compound is employed in various biological assays and experiments. Its specific inhibitory action makes it useful for dissecting cellular signalling pathways and understanding the impact of cholinesterase modulation.
Pharmacological Research
This chemical is valuable in pharmacological investigations aimed at understanding the effects of cholinesterase inhibition. Researchers use it to explore potential therapeutic targets and mechanisms related to neurological functions and disorders.
| Molecular weight | 342.36 |
|---|---|
| Empirical formula | C12H32N4O3P2 |
| Storage temperature | −20°C |

Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ACHE(43), BCHE(590) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetraisopropyl pyrophosphoramide used for?
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Tetraisopropyl pyrophosphoramide is primarily used as a potent inhibitor of cholinesterase enzymes, specifically human acetylcholinesterase (ACHE) and butyrylcholinesterase (BCHE). It serves as a valuable tool in biochemical research, cell biology, and pharmacological studies investigating enzyme kinetics and function.
What are the CAS number and formula for Tetraisopropyl pyrophosphoramide?
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The CAS number for Tetraisopropyl pyrophosphoramide is 513-00-8, and its molecular formula is C12H32N4O3P2.
What grade and purity does Tech Serve Solutions supply for Tetraisopropyl pyrophosphoramide?
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Tech Serve Solutions supplies Tetraisopropyl pyrophosphoramide. The specific grade and purity are available upon request or via product specification sheets. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Tetraisopropyl pyrophosphoramide be handled safely?
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Tetraisopropyl pyrophosphoramide is a dangerous substance labelled with GHS06, bearing the signal word 'Danger'. It carries hazard statements H300 (Fatal if swallowed), H310 (Fatal in contact with skin), and H330 (Fatal if inhaled). Strict adherence to safety protocols, including the use of appropriate personal protective equipment such as eyeshields, faceshields, gloves, and respiratory protection (e.g., N100 respirators or P3 filter cartridges), is essential during handling.
Is Tetraisopropyl pyrophosphoramide a controlled substance?
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The provided data does not indicate that Tetraisopropyl pyrophosphoramide is a controlled or scheduled substance. However, users should always verify local regulations.
How is Tetraisopropyl pyrophosphoramide packaged and shipped?
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Tetraisopropyl pyrophosphoramide is handled with care according to its hazard classification. It is shipped as UN 2811, Hazard Class 6.1, Packing Group I. Specific packaging details for export are available upon enquiry.
How can I request a quote or sample for Tetraisopropyl pyrophosphoramide?
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To request a quote or a sample of Tetraisopropyl pyrophosphoramide, please contact the Tech Serve Solutions sales team through our website or designated contact channels, providing your specific requirements.
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