5-Iodo-1,2,3-trimethoxybenzene
5-Iodo-1,2,3-trimethoxybenzene (CAS: 25245-29-8) is a halogenated aromatic compound with the molecular formula C9H11IO3 and a molecular weight of 294.09 g/mol. This iodinated derivative of 1,2,3-trimethoxybenzene serves as a valuable building block in organic synthesis. It is frequently employed in the preparation of more complex molecules within research and development settings, particularly in the fields of medicinal chemistry and materials science.
- IUPAC
- 3,4,5-Trimethoxyiodobenzene
- Synonyms
- 25245-29-8C9H11IO33,4,5-Trimethoxyiodobenzene

Organic Synthesis Intermediate
5-Iodo-1,2,3-trimethoxybenzene is utilised as a key intermediate in the synthesis of complex organic molecules. Its iodo-substituent allows for various cross-coupling reactions and nucleophilic substitutions.
Pharmaceutical Research
This compound can be incorporated into synthetic routes for novel pharmaceutical agents. Its structure provides a scaffold for developing potential drug candidates.
Materials Science
It may be used in the development of advanced materials, where its aromatic and halogenated nature can influence electronic or optical properties.
| Molecular weight | 294.09 |
|---|---|
| Empirical formula | C9H11IO3 |
| Assay | ≥97.0% (GC) |

Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Iodo-1,2,3-trimethoxybenzene used for?
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5-Iodo-1,2,3-trimethoxybenzene is primarily used as a building block in organic synthesis for preparing more complex molecules, particularly in pharmaceutical research and materials science.
What are the CAS number and formula for 5-Iodo-1,2,3-trimethoxybenzene?
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The CAS number is 25245-29-8, and the empirical formula is C9H11IO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Iodo-1,2,3-trimethoxybenzene with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should 5-Iodo-1,2,3-trimethoxybenzene be handled safely?
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Due to its irritant properties (H315, H319, H335) and potential for skin sensitisation (H317), handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, face shields, and gloves. Ensure adequate ventilation. Refer to the safety data sheet for comprehensive guidance.
How is 5-Iodo-1,2,3-trimethoxybenzene packed and shipped?
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5-Iodo-1,2,3-trimethoxybenzene is carefully packed for secure transport and can be exported globally by Tech Serve Solutions. Please contact us for specific shipping details.
How can I request a sample or quote for 5-Iodo-1,2,3-trimethoxybenzene?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via our website or direct email, providing the product name and CAS number (25245-29-8).
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