N,N-Dimethylformamide
N,N-Dimethylformamide (CAS: 68-12-2), with the linear formula HCON(CH3)2 and a molecular weight of 73.09 g/mol, is a versatile polar aprotic solvent. It is widely utilised for dissolving a broad spectrum of hydrophobic organic compounds and is particularly noted for its utility as a solvent for chromogenic substrates in molecular biology. Its ability to solvate diverse substances makes it an essential component in various chemical synthesis processes.
- IUPAC
- DMF
- Synonyms
- HCON(CH3)2DimethylformamideDMFFormic acid dimethylamide
General Solvent Applications
N,N-Dimethylformamide serves as an excellent solvent for numerous hydrophobic organic compounds due to its polar aprotic nature. It is broadly applied across various chemical industries for synthesis and formulation processes.
Molecular Biology Reagent
This compound is suitable as a solvent for chromogenic substrates, such as X-Gal, which are commonly used in molecular biology applications for detecting enzyme activity or gene expression.
Chemical Synthesis
As a versatile building block and solvent, DMF is integral to many organic synthesis pathways. Its properties facilitate a range of reactions, making it a staple in research and development laboratories.
| Molecular weight | 73.09 |
|---|---|
| Linear formula | HCON(CH3)2 |
| Assay | ≥99.8% (GC) |
| Boiling point | 153 °C(lit.) |
| Density | 0.944 g/mL(lit.) |
| Refractive index | n20/D 1.430(lit.) |
| Vapour pressure | 2.7 mmHg (20 °C) |
| Melting point | −61 °C(lit.) |
| Vapour density | 2.5 (vs air) |
| Autoignition temp | 833 °F |
| Storage temperature | room temp |
| Impurities tested | ≤0.0002% amines (as dimethylamine)≤0.001% non-volatile matter≤0.02% water (Karl Fischer) |
| Application | Solvent for many hydrophobic organic compounds. |
| Suitability | suitable for solvent for chromogenic substrates (X-Gal, etc.) used in molecular biology applications. |
Hazard statements
- H226Flammable liquid and vapour
- H312Harmful in contact with skin
- H319Causes serious eye irritation
- H360D
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 2265 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-20/21-36 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 15.2 % |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethylformamide (CAS 68-12-2) used for?
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N,N-Dimethylformamide is primarily used as a solvent for many hydrophobic organic compounds and is suitable for use with chromogenic substrates in molecular biology. It is also a common reagent in chemical synthesis.
What is the CAS number and formula for N,N-Dimethylformamide?
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The CAS number for N,N-Dimethylformamide is 68-12-2, and its linear formula is HCON(CH3)2.
What grade and purity does Tech Serve Solutions supply for N,N-Dimethylformamide?
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Tech Serve Solutions supplies N,N-Dimethylformamide with an assay of ≥99.8% (GC). We do not represent this product as USP, BP, or EP grade.
How should N,N-Dimethylformamide be handled safely?
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N,N-Dimethylformamide is a flammable liquid and vapour (H226), harmful if swallowed or inhaled (H312 + H332), causes serious eye irritation (H319), and may damage fertility or the unborn child (H360D). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and keep away from ignition sources.
Is N,N-Dimethylformamide packed and exported by TSS?
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Yes, N,N-Dimethylformamide is packed and available for export by Tech Serve Solutions.
How can I request a quote or sample for N,N-Dimethylformamide?
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To request a quote or sample for N,N-Dimethylformamide, please contact our sales team via the website or direct inquiry.
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