N,N-Dimethylformamide di-tert-butyl acetal
N,N-Dimethylformamide di-tert-butyl acetal (CAS: 36805-97-7) is a unique acetal compound with the linear formula (CH3)2NCH[OC(CH3)3]2 and a molecular weight of 203.32 g/mol. This reagent is valuable in organic synthesis, particularly for the introduction of protected dimethylaminomethylene groups. Its specific reactivity makes it a useful building block in the preparation of various complex organic molecules and pharmaceutical intermediates.
- IUPAC
- 1,1-Di-tert-butoxy-N,N-dimethylmethylamine,1,1-Di-tert-butoxytrimethylamine
- Synonyms
- (CH3)2NCH[OC(CH3)3]21,1-Di-tert-butoxy-N,N-dimethylmethylamine1,1-Di-tert-butoxytrimethylamine
![N,N-Dimethylformamide di-tert-butyl acetal ((CH3)2NCH[OC(CH3)3]2) — chemical structure, CAS 36805-97-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F36805-97-7.png&w=3840&q=75)
Protecting Group Introduction
N,N-Dimethylformamide di-tert-butyl acetal serves as a convenient reagent for the introduction of the dimethylaminomethylene protecting group onto various nucleophiles, such as amines and alcohols. This protection strategy is essential in multi-step organic syntheses.
Synthesis of Heterocycles
This acetal can be employed in the construction of nitrogen-containing heterocyclic compounds. Its structure allows for cyclisation reactions, leading to the formation of diverse heterocyclic scaffolds relevant in medicinal chemistry.
Organic Building Block
As a versatile building block, it facilitates the creation of more complex molecular architectures. Its utility spans various areas of fine chemical synthesis and research laboratories.
| Molecular weight | 203.32 |
|---|---|
| Linear formula | (CH3)2NCH[OC(CH3)3]2 |
| Grade | technical |
| Boiling point | 56-57 °C/8 mmHg(lit.) |
| Density | 0.848 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethylformamide di-tert-butyl acetal used for?
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N,N-Dimethylformamide di-tert-butyl acetal is primarily used as a reagent in organic synthesis for introducing dimethylaminomethylene protecting groups and as a building block for constructing complex organic molecules, including heterocyclic compounds.
What are the CAS number and formula for N,N-Dimethylformamide di-tert-butyl acetal?
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The CAS number is 36805-97-7 and the linear formula is (CH3)2NCH[OC(CH3)3]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Dimethylformamide di-tert-butyl acetal in technical grade. We do not represent this product as meeting USP, BP, or EP standards.
How should N,N-Dimethylformamide di-tert-butyl acetal be handled safely?
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N,N-Dimethylformamide di-tert-butyl acetal is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment including safety glasses, gloves, and a respirator.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports N,N-Dimethylformamide di-tert-butyl acetal globally, adhering to all relevant international regulations for hazardous materials. Details on specific packaging for your order will be provided upon inquiry.
How can I request a sample or quote for N,N-Dimethylformamide di-tert-butyl acetal?
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To request a sample or quote for N,N-Dimethylformamide di-tert-butyl acetal, please contact our sales team directly through the website or by phone. Provide your specific requirements for prompt service.
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