N,N-Dimethylformamide dimethyl acetal
N,N-Dimethylformamide dimethyl acetal (CAS 4637-24-5), with the molecular formula (CH3)2NCH(OCH3)2 and a molar mass of 119.16 g/mol, is a valuable organic synthesis reagent. This acetal serves primarily as a derivatization agent for analytical purposes, particularly in gas chromatography and GC-MS. It is widely employed for the derivatisation of primary sulfonamides and trifluoroacetic acid, enabling their detection and quantification. Tech Serve Solutions offers this compound for research and laboratory applications.
- IUPAC
- 1,1-Dimethoxytrimethylamine,1,1-Dimethoxy-N,N-dimethylmethylamine
- Synonyms
- (CH3)2NCH(OCH3)21,1-Dimethoxytrimethylamine1,1-Dimethoxy-N,N-dimethylmethylamine
Derivatisation Reagent for Sulfonamides
N,N-Dimethylformamide dimethyl acetal is utilised for the derivatisation of primary sulfonamides. This process enhances their volatility and detectability in analytical techniques like gas chromatography.
Esterification Agent
This compound can be employed in esterification reactions. Its acetal structure facilitates the introduction of specific functional groups, contributing to organic synthesis.
GC and GC-MS Analysis
Its primary application is as a derivatisation reagent for gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). It is particularly effective for derivatising trifluoroacetic acid and primary sulfonamides prior to analysis.
Organic Synthesis Building Block
As an acetal and an amide derivative, it functions as a versatile building block in organic synthesis, enabling C-C bond formation and other transformations.
| Molecular weight | 119.16 |
|---|---|
| Linear formula | (CH3)2NCH(OCH3)2 |
| Assay | 94% |
| Grade | for derivatization (GC/GC-MS) |
| Boiling point | 102-103 °C/720 mmHg(lit.) |
| Density | 0.897 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.396(lit.) |
| Application | Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid. |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 5 °C / 41 °F |
| Transport (UN / ADR) | UN 3271 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-22-36/37/38 |
| Safety statements (S) | 16-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Derivatization Reagent For | AcetylationsEsterifications |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethylformamide dimethyl acetal used for?
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N,N-Dimethylformamide dimethyl acetal (CAS 4637-24-5) is primarily used as a derivatisation reagent for analytical purposes, especially in GC and GC-MS. It is suitable for the derivatisation of primary sulfonamides and trifluoroacetic acid, and can also be used in esterification reactions.
What are the CAS number and molecular formula for N,N-Dimethylformamide dimethyl acetal?
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The CAS number for N,N-Dimethylformamide dimethyl acetal is 4637-24-5, and its molecular formula is (CH3)2NCH(OCH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Dimethylformamide dimethyl acetal with an assay of 94%, specified for derivatisation (GC/GC-MS).
What are the main safety hazards associated with N,N-Dimethylformamide dimethyl acetal?
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N,N-Dimethylformamide dimethyl acetal is a highly flammable liquid and vapour (H225). It is harmful if swallowed (H302) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including safety glasses, gloves, and suitable respiratory protection, should be used when handling this chemical.
How is N,N-Dimethylformamide dimethyl acetal packed, shipped, and exported?
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N,N-Dimethylformamide dimethyl acetal is packed and shipped in accordance with international regulations for hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide.
How can I request a quote or sample for N,N-Dimethylformamide dimethyl acetal?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly with your specific requirements.
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