2,5-Difluorophenylacetic acid
2,5-Difluorophenylacetic acid (CAS: 85068-27-5) is a fluorinated organic building block with the linear formula F₂C₆H₃CH₂CO₂H and a molecular weight of 172.13 g/mol. This carboxylic acid is a valuable intermediate in organic synthesis, particularly for introducing the 2,5-difluorophenylacetyl moiety into more complex molecules. Its utility spans various chemical research and development sectors, serving as a key component in the construction of novel organic compounds.
- Synonyms
- F2C6H3CH2CO2H
Synthesis of Pharmaceutical Intermediates
2,5-Difluorophenylacetic acid is employed in multi-step syntheses to create advanced intermediates for potential pharmaceutical agents. The difluorinated phenylacetic acid scaffold can influence lipophilicity and metabolic stability in drug discovery programs.
Agrochemical Research
This compound serves as a building block in the development of new agrochemicals. Its fluorinated aromatic ring can impart specific biological activities or modify the properties of candidate pesticides or herbicides.
Materials Science
Fluorinated organic compounds like 2,5-Difluorophenylacetic acid can be investigated for their use in advanced materials. They may serve as precursors or modifiers in the creation of polymers or specialty organic materials with unique electronic or physical properties.
Organic Synthesis Reagent
As a readily available functionalised molecule, 2,5-Difluorophenylacetic acid is used in general organic synthesis to introduce the 2,5-difluorophenylacetic acid group via standard carboxylic acid reactions, such as esterification or amidation.
| Molecular weight | 172.13 |
|---|---|
| Linear formula | F2C6H3CH2CO2H |
| Assay | 95% |
| Application | 2,5-Difluorophenylacetic acid has been used in the synthesis of 2,2-dimethyl-4-(2,5-difluorophenyl)-5-[4-(aminosulfonyl)phenyl]-3(2H)-furanone1. |
| Melting point | 126-128 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluorophenylacetic acid primarily used for?
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2,5-Difluorophenylacetic acid is primarily used as a building block in organic synthesis for the preparation of more complex molecules, including potential pharmaceutical intermediates and agrochemicals.
What are the CAS number and formula for 2,5-Difluorophenylacetic acid?
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The CAS number is 85068-27-5 and the linear formula is F₂C₆H₃CH₂CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Difluorophenylacetic acid with an assay of 95%. This is a technical/research grade; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the main safety hazards associated with 2,5-Difluorophenylacetic acid?
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2,5-Difluorophenylacetic acid is classified with the GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (N95), should be used.
How is 2,5-Difluorophenylacetic acid typically packed and exported?
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2,5-Difluorophenylacetic acid is carefully packed to maintain its integrity during transit. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a quote or sample for 2,5-Difluorophenylacetic acid?
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Please contact the Tech Serve Solutions sales team via our website or direct contact details to request a quotation or a sample of 2,5-Difluorophenylacetic acid.
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