2,5-Difluoropyridine
2,5-Difluoropyridine (CAS 84476-99-3), with the molecular formula C5H3F2N and a molecular weight of 115.08 g/mol, is a fluorinated heterocyclic compound. It serves as a valuable building block in organic synthesis, particularly for the creation of more complex molecules in the pharmaceutical and agrochemical sectors. Its specific reactivity is leveraged in various chemical research and development processes.
- Synonyms
- C5H3F2N

Pharmaceutical Intermediates
Used in the synthesis of active pharmaceutical ingredients (APIs) where the difluoropyridine moiety is incorporated into the final drug structure to modulate properties like efficacy or metabolic stability.
Agrochemical Development
A key intermediate in the development of new pesticides and herbicides, contributing to the creation of novel crop protection agents with enhanced performance.
Material Science Research
Investigated for its potential use in the development of advanced materials, including functional polymers and organic electronics.
Chemical Synthesis Reagent
Employed as a versatile reagent in academic and industrial research for constructing complex organic molecules and exploring novel reaction pathways.
| Molecular weight | 115.08 |
|---|---|
| Empirical formula | C5H3F2N |
| Assay | 97% |
| Density | 1.274 g/mL at 25 °C |
| Refractive index | n20/D 1.445 |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 24 °C / 75.2 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluoropyridine used for?
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2,5-Difluoropyridine is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and formula for 2,5-Difluoropyridine?
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The CAS number for 2,5-Difluoropyridine is 84476-99-3, and its empirical formula is C5H3F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Difluoropyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2,5-Difluoropyridine be handled safely?
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2,5-Difluoropyridine is a flammable liquid and vapour (H226) and causes skin (H315), serious eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area, keeping it away from ignition sources.
Is 2,5-Difluoropyridine suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,5-Difluoropyridine, adhering to all necessary shipping regulations (UN 1993, Class 3, Packing Group III).
How can I request a sample or quote for 2,5-Difluoropyridine?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing your specific requirements.
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