2,5-Difluorophenol
2,5-Difluorophenol (CAS: 2713-31-7) is a valuable organic intermediate with the molecular formula F2C6H3OH and a molecular weight of 130.09 g/mol. This fluorinated aromatic compound serves as a key building block in chemical synthesis, particularly for the creation of specialised fluorinated molecules. Its applications span various research and development areas, contributing to advancements in materials science and organic chemistry.
- Synonyms
- F2C6H3OH

Synthesis of Fluorinated Acids
2,5-Difluorophenol is utilised in the synthesis of di- or trifluorinated hydroxybenzoic acids. These derivatives can serve as precursors for more complex fluorinated organic compounds.
Organic Synthesis Intermediate
As a difluorinated phenol, it acts as a versatile building block for introducing fluorine atoms into organic structures. This is crucial in the development of novel molecules with tailored properties.
Research and Development
This compound is employed in research settings for exploring new synthetic pathways and developing innovative chemical entities. Its specific structure makes it useful in structure-activity relationship studies.
| Molecular weight | 130.09 |
|---|---|
| Linear formula | F2C6H3OH |
| Assay | 95% |
| Application | 2,5-Difluorophenol has been used in the synthesis of di- or trifluorinated hydroxybenzoic acids1. |
| Melting point | 40-42 °C(lit.) |


Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 53 °C / 127.4 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22-36/37/38 |
| Safety statements (S) | 16-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluorophenol used for?
+
2,5-Difluorophenol is primarily used as an intermediate in organic synthesis, particularly for the preparation of di- or trifluorinated hydroxybenzoic acids and other fluorinated organic compounds.
What is the CAS number and molecular formula for 2,5-Difluorophenol?
+
The CAS number for 2,5-Difluorophenol is 2713-31-7, and its molecular formula is F2C6H3OH.
What grade and purity does Tech Serve Solutions supply for 2,5-Difluorophenol?
+
Tech Serve Solutions supplies 2,5-Difluorophenol with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with 2,5-Difluorophenol?
+
2,5-Difluorophenol is a flammable solid and is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment.
Is 2,5-Difluorophenol available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,5-Difluorophenol.
How can I request a sample or quote for 2,5-Difluorophenol?
+
Please contact our sales team via the website or direct phone line to request a sample or a quotation for 2,5-Difluorophenol.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis