2,5-Difluoroiodobenzene
2,5-Difluoroiodobenzene (CAS: 2265-92-1) is a fluorinated aromatic compound with a molecular weight of 239.99 g/mol. This halogenated hydrocarbon serves as a versatile building block in organic synthesis. Its structure, featuring both fluorine and iodine substituents on a benzene ring, allows for diverse chemical transformations. It is frequently employed in the preparation of more complex fluorinated organic molecules for various industrial and research applications.
- Synonyms
- F2C6H3I1-Iodo-2,5-difluorobenzene

Organic Synthesis Intermediate
2,5-Difluoroiodobenzene is a key intermediate in the synthesis of complex organic molecules. Its reactive iodine atom can participate in various coupling reactions, while the fluorine atoms influence the electronic properties of the resulting compounds.
Pharmaceutical Research
This compound is utilised in the development of novel pharmaceutical agents. The incorporation of fluorine atoms can modulate a drug candidate's metabolic stability, lipophilicity, and binding affinity.
Agrochemical Development
It serves as a building block for creating new agrochemicals, such as pesticides and herbicides. Fluorinated compounds often exhibit enhanced biological activity and environmental persistence profiles.
Materials Science
2,5-Difluoroiodobenzene can be used in the synthesis of advanced materials, including polymers and liquid crystals, where the unique properties imparted by fluorine are desirable.
| Molecular weight | 239.99 |
|---|---|
| Linear formula | F2C6H3I |
| Assay | 97% |
| Boiling point | 178-179 °C(lit.) |
| Density | 1.998 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5600(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluoroiodobenzene used for?
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2,5-Difluoroiodobenzene is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its structure allows for versatile chemical transformations.
What is the CAS number and formula for 2,5-Difluoroiodobenzene?
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The CAS number is 2265-92-1 and the linear formula is F₂C₆H₃I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Difluoroiodobenzene with an assay of 97%. TSS does not represent this product as USP, BP, or EP grade.
How should 2,5-Difluoroiodobenzene be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. It is a combustible liquid with a flash point of 85°C (185°F).
How is 2,5-Difluoroiodobenzene packed, shipped, and exported?
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2,5-Difluoroiodobenzene is packed according to relevant shipping regulations, including its classification as NA 1993 / PGIII. TSS is an experienced global exporter of fine chemicals.
How can I request a sample or quote for 2,5-Difluoroiodobenzene?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or direct contact information.
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