4-(Trifluoromethyl)-N-methylaniline
4-(Trifluoromethyl)-N-methylaniline (CAS: 22864-65-9; Formula: C8H8F3N) is a fluorinated aromatic amine with a molecular weight of 175.15 g/mol. It is a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its trifluoromethyl group imparts unique electronic and lipophilic properties, making it a sought-after building block for advanced chemical research and development.
Pharmaceutical Intermediate
This compound serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its trifluoromethyl moiety can enhance drug efficacy and metabolic stability.
Agrochemical Synthesis
It is utilised in the development of novel pesticides and herbicides, where the fluorinated structure can contribute to biological activity and environmental persistence.
Organic Synthesis Reagent
As a versatile building block, 4-(Trifluoromethyl)-N-methylaniline is employed in various organic transformations to introduce the trifluoromethylaniline fragment into target molecules.
Materials Science
Potential applications exist in the development of specialty polymers and advanced materials where its unique electronic properties can be exploited.
| Molecular weight | 175.15 |
|---|---|
| Empirical formula | C8H8F3N |
| Assay | 97% |
| Boiling point | 105-106 °C/20 mmHg(lit.) |
| Density | 1.2394 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4888(lit.) |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)-N-methylaniline used for?
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4-(Trifluoromethyl)-N-methylaniline is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other complex organic molecules. It is also a valuable building block in organic synthesis and potentially in materials science.
What are the CAS number and formula for 4-(Trifluoromethyl)-N-methylaniline?
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The CAS number for 4-(Trifluoromethyl)-N-methylaniline is 22864-65-9, and its molecular formula is C8H8F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)-N-methylaniline with an assay of 97%. This product is typically considered a research or technical grade; TSS does not represent it as USP, BP, or EP grade.
How should 4-(Trifluoromethyl)-N-methylaniline be handled?
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4-(Trifluoromethyl)-N-methylaniline is classified as harmful if swallowed and may cause an allergic skin reaction (H302, H317). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used during handling. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is 4-(Trifluoromethyl)-N-methylaniline packaged, shipped, and exported?
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Tech Serve Solutions offers various packaging options to meet customer requirements for laboratory and industrial scales. We are experienced in global shipping and export procedures for fine chemicals.
How can I request a sample or quote for 4-(Trifluoromethyl)-N-methylaniline?
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To request a sample or a quote, please use the contact form on our website or email our sales department, providing the product name and CAS number (22864-65-9).
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