4-(Trifluoromethyl)-D-phenylalanine
4-(Trifluoromethyl)-D-phenylalanine (CAS: 114872-99-0) is a non-proteinogenic amino acid derivative with the molecular formula C10H10F3NO2 and a molecular weight of 233.19 g/mol. As an unnatural amino acid, it finds utility in chemical biology and peptide chemistry for modifying peptide structures and functions. It is a valuable building block for creating novel biomolecules and peptidomimetics in research and development.
- IUPAC
- (R)-2-Amino-3-[4-(trifluoromethyl)phenyl]propionic acid
Peptide Synthesis
Incorporation into peptides to introduce unique structural or functional properties due to the trifluoromethyl group. This unnatural amino acid derivative can enhance metabolic stability or alter binding affinities of the resulting peptides.
Chemical Biology Research
Used as a probe or building block in chemical biology to investigate biological pathways or protein interactions. Its distinct structure aids in the development of novel biochemical tools.
Drug Discovery and Development
Serves as an intermediate or scaffold in the synthesis of potential pharmaceutical compounds. The trifluoromethyl moiety can influence pharmacokinetic properties like lipophilicity and metabolic resistance.
Materials Science
Explored for incorporation into novel polymers or biomaterials where its specific chemical properties can impart desired characteristics.
| Molecular weight | 233.19 |
|---|---|
| Empirical formula | C10H10F3NO2 |
| Assay | ≥98.5% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)-D-phenylalanine used for?
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4-(Trifluoromethyl)-D-phenylalanine is primarily used in peptide synthesis, chemical biology research, and as an intermediate in drug discovery, owing to its unnatural amino acid structure featuring a trifluoromethyl group.
What are the CAS number and formula for 4-(Trifluoromethyl)-D-phenylalanine?
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The CAS number is 114872-99-0, and the empirical formula is C10H10F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)-D-phenylalanine with an assay of ≥98.5% (HPLC). This product is typically supplied for research purposes and is not represented as USP, BP, EP, or food grade.
What are the safety and handling considerations for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with a WGK Germany of 3, indicating a high hazard to water.
Is this chemical controlled or scheduled?
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The provided data does not indicate that 4-(Trifluoromethyl)-D-phenylalanine (CAS: 114872-99-0) is a controlled or scheduled substance.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are packed and shipped in compliance with international shipping regulations for chemical substances.
How can I request a sample or quote for 4-(Trifluoromethyl)-D-phenylalanine?
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Please contact our sales team via the website or direct email to request a quotation or sample for 4-(Trifluoromethyl)-D-phenylalanine (CAS: 114872-99-0).
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