1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene
1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene (CAS: 378787-34-9) is a silicon-containing organic compound with a molecular weight of 329.35 g/mol. It functions as a protected phenol and serves as a valuable building block in organic synthesis. This compound is typically employed in the construction of more complex molecular architectures, particularly where a protected hydroxyl group on an aromatic ring is required during synthetic transformations.
- IUPAC
- (2-Bromophenoxy)triisopropylsilane
![1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene (C15H25BrOSi) — chemical structure, CAS 378787-34-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F378787-34-9.png&w=3840&q=75)
Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic synthesis pathways. Its structure allows for selective reactions on other parts of the molecule while the phenolic hydroxyl group remains protected by the bulky triisopropylsilyl (TIPS) ether.
Building Block for Complex Molecules
Serves as a versatile building block for the synthesis of diverse organic compounds, including pharmaceuticals and advanced materials. The bromo-substituent offers a handle for various cross-coupling reactions.
Protected Phenol Derivative
The triisopropylsilyl ether moiety protects the phenolic hydroxyl group, enabling transformations elsewhere in the molecule. This protection can be subsequently removed under specific conditions.
| Molecular weight | 329.35 |
|---|---|
| Empirical formula | C15H25BrOSi |
| Assay | 97% |
| Boiling point | 320-328 °C |
| Density | 1.162 g/mL at 25 °C |
| Refractive index | n20/D 1.525 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene used for?
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This compound is primarily used as a building block and intermediate in organic synthesis, serving as a protected phenol derivative for constructing more complex molecules.
What is the CAS number and formula for 1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene?
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The CAS number is 378787-34-9 and the empirical formula (Hill notation) is C15H25BrOSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This is a technical/research grade material, and we do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene be handled safely?
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According to GHS, this compound is a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes and remove contact lenses, if present and easy to do. Continue rinsing.
Is 1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is this chemical packed and exported by TSS?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging for safe transit and adheres to all necessary export regulations for chemical shipments.
How can I request a sample or quote for 1-Bromo-2-[tris(1-methylethyl)silyloxy]benzene?
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Please contact our sales team via the website or by phone to request a sample or a formal quotation.
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