1-Bromo-2-(trifluoromethoxy)ethane
1-Bromo-2-(trifluoromethoxy)ethane (CAS: 1645-93-8), with the molecular formula C3H4BrF3O and a molecular weight of 192.96 g/mol, is a valuable halogenated organic compound. It serves as a key building block in organic synthesis, particularly for introducing the trifluoromethoxyethyl moiety into target molecules. Its applications span various research and development sectors, including pharmaceuticals and materials science, where precise chemical structures are paramount.
- IUPAC
- 2-Bromoethyl trifluoromethyl ether
- Synonyms
- 2-Bromoethyl trifluoromethyl ether

Organic Synthesis Intermediate
This compound is utilised as a versatile intermediate in the synthesis of complex organic molecules. Its structure allows for selective reactions to build more intricate chemical architectures.
Fluorinated Building Block
As a fluorinated building block, it is instrumental in creating novel compounds with altered physical and chemical properties conferred by the trifluoromethoxy group.
Pharmaceutical Research
Its unique structural features make it a candidate for incorporation into potential pharmaceutical agents during drug discovery and development processes.
Materials Science
1-Bromo-2-(trifluoromethoxy)ethane can be employed in the development of advanced materials where specific functional groups are required to achieve desired performance characteristics.
| Molecular weight | 192.96 |
|---|---|
| Empirical formula | C3H4BrF3O |
| Density | 1.674 g/mL at 25 °C |
| Refractive index | n20/D 1.367 |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | 110 °C / 230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2-(trifluoromethoxy)ethane used for?
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1-Bromo-2-(trifluoromethoxy)ethane is used as a building block in organic synthesis and for introducing the trifluoromethoxyethyl group into various molecules, particularly in pharmaceutical research and materials science.
What are the CAS number and chemical formula for 1-Bromo-2-(trifluoromethoxy)ethane?
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The CAS number is 1645-93-8, and the chemical formula is C3H4BrF3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The exact grade and purity are available upon request, and it is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 1-Bromo-2-(trifluoromethoxy)ethane be handled?
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1-Bromo-2-(trifluoromethoxy)ethane is a Warning substance that is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment (P261, P280) and ensure good ventilation. Avoid contact with eyes (P305 + P351 + P338).
Is 1-Bromo-2-(trifluoromethoxy)ethane a controlled substance?
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The provided data does not indicate that 1-Bromo-2-(trifluoromethoxy)ethane is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific shipping and export details for 1-Bromo-2-(trifluoromethoxy)ethane can be provided by our sales team upon inquiry.
How can I request a quote or sample?
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To request a quote or sample of 1-Bromo-2-(trifluoromethoxy)ethane, please contact our sales department through the TSS website or direct contact details.
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