1-Boc-L-prolinamide
1-Boc-L-prolinamide (CAS: 35150-07-3) is a derivative of the amino acid proline, with the chemical formula C10H18N2O3 and a molecular weight of 214.26 g/mol. This compound serves as a valuable building block in organic synthesis and peptide chemistry. Its protected nature allows for controlled reactions, making it useful in the development of complex molecules and pharmaceutical intermediates.
- IUPAC
- (S)-2-(Aminocarbonyl)-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester,N-(tert-Butoxycarbonyl)proline amide

Peptide Synthesis
1-Boc-L-prolinamide is employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. The tert-butoxycarbonyl (Boc) protecting group facilitates controlled coupling reactions.
Organic Synthesis Intermediate
This compound acts as a versatile intermediate in the synthesis of various organic molecules. Its structure is often incorporated into the design of new chemical entities and pharmaceutical candidates.
Chemical Biology Research
Utilised in chemical biology for constructing peptidomimetics or modified peptides. Its specific stereochemistry and functional groups are leveraged for biochemical studies.
| Molecular weight | 214.26 |
|---|---|
| Empirical formula | C10H18N2O3 |
| Assay | 97% |
| Melting point | 104-108 °C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-L-prolinamide used for?
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1-Boc-L-prolinamide is primarily used as an intermediate in peptide synthesis and organic synthesis, particularly in the development of pharmaceutical candidates and in chemical biology research.
What is the CAS number and chemical formula for 1-Boc-L-prolinamide?
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The CAS number is 35150-07-3, and the chemical formula is C10H18N2O3.
What grade and purity does Tech Serve Solutions supply for 1-Boc-L-prolinamide?
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Tech Serve Solutions supplies 1-Boc-L-prolinamide with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should 1-Boc-L-prolinamide be handled safely?
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1-Boc-L-prolinamide is classified as harmful if swallowed (H302). When handling, it is recommended to wear a dust mask (type N95 US recommended), eye shields, and gloves. Ensure adequate ventilation.
Is 1-Boc-L-prolinamide a controlled substance?
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The provided data does not indicate that 1-Boc-L-prolinamide (CAS: 35150-07-3) is a controlled substance.
How is 1-Boc-L-prolinamide packed and shipped?
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Tech Serve Solutions packs and exports fine chemicals, including 1-Boc-L-prolinamide, following appropriate safety and regulatory guidelines for global distribution.
How can I request a quote or sample of 1-Boc-L-prolinamide?
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Please contact the Tech Serve Solutions sales team directly through our website or by phone to request a quotation or a product sample.
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