SB-366791
SB-366791 (CAS: 472981-92-3), a chemical compound with the formula C16H14NO2Cl and a molecular weight of 287.74 g/mol, is supplied as a white to tan powder. This substance serves as a valuable tool in neurobiology and cell signalling research, particularly in studies involving the vanilloid receptor TRPV1. It is a key research chemical for investigating cellular pathways and potential therapeutic targets.
- IUPAC
- N-(3-Methoxyphenyl)-4-chlorocinnamide

TRPV1 Receptor Research
SB-366791 is recognised as a selective TRPV1 antagonist. This makes it an essential reagent for researchers studying the function and modulation of the transient receptor potential vanilloid 1 (TRPV1) channel, which plays a critical role in pain sensation and thermosensation.
Neuroscience and Cell Signalling Studies
Its application extends to cellular neuroscience and broader cell signalling research. As a bioactive small molecule, it aids in dissecting complex signalling cascades within neurons and other cell types.
Drug Discovery and Development
SB-366791 is an approved therapeutic/drug candidate, indicating its potential in pharmaceutical research. It serves as a reference compound or lead structure in the early stages of drug discovery and development programmes.
| Molecular weight | 287.74 |
|---|---|
| Empirical formula | C16H14NO2Cl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: soluble ≥10 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... TRPV1(7442) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB-366791 used for?
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SB-366791 is primarily used in research for its role as a selective TRPV1 antagonist, aiding studies in neuroscience, cell signalling, and pain research. It is also an approved therapeutic/drug candidate for further investigation.
What is the CAS number and formula for SB-366791?
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The CAS number for SB-366791 is 472981-92-3, and its chemical formula is C16H14NO2Cl.
What grade and purity does Tech Serve Solutions supply for SB-366791?
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Tech Serve Solutions supplies SB-366791 with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should SB-366791 be handled and stored?
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Handle SB-366791 with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. According to WGK Germany, it is classified as hazard class 3. Store in a cool, dry place.
Is SB-366791 available for export?
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Yes, Tech Serve Solutions exports and supplies SB-366791 globally to research institutions and pharmaceutical companies.
How can I request a quote or sample of SB-366791?
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To request a quote or sample of SB-366791, please contact our sales department through the TSS website or via direct inquiry.
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