SB-505124 hydrochloride hydrate
SB-505124 hydrochloride hydrate (CAS 694433-59-5 free base) is a yellow powder with a molecular weight of 335.40 (anhydrous free base basis). This compound functions as a selective inhibitor, primarily investigated for its role in TGF-β pathway modulation. It is employed in research settings to study developmental processes and cellular differentiation. Tech Serve Solutions supplies this chemical with an assay of ≥98% (HPLC), suitable for research applications.
- IUPAC
- 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride hydrate
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TGF-β Pathway Research
SB-505124 hydrochloride hydrate has been utilised in studies focusing on the Transforming Growth Factor-beta (TGF-β) signalling pathway. It serves as a tool to investigate the pathway's involvement in various biological processes.
Cellular Differentiation Studies
This compound aids in research exploring cellular differentiation. Its inhibitory action on the TGF-β type I receptor kinase (ALK5) allows for detailed examination of differentiation mechanisms.
Drug Candidate Research
As an approved therapeutic/drug candidate, SB-505124 hydrochloride hydrate is a subject of interest in pharmaceutical research. Its potential therapeutic applications are explored in preclinical research settings.
| Molecular weight | 335.40 (anhydrous free base basis) |
|---|---|
| Empirical formula | C20H21N3O2 · xHCl · yH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Application | SB-505124 hydrochloride hydrate was used to study the role of TGF-β pathway in development and differentiation studies.3,4 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB-505124 hydrochloride hydrate used for?
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SB-505124 hydrochloride hydrate is used in research, particularly for studying the TGF-β pathway and its role in development and differentiation. It is classified as an approved therapeutic/drug candidate and a bioactive small molecule.
What are the CAS number and formula for SB-505124 hydrochloride hydrate?
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The CAS number for the free base is 694433-59-5. The empirical formula is C20H21N3O2 · xHCl · yH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB-505124 hydrochloride hydrate with an assay of ≥98% (HPLC). This product is supplied for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should SB-505124 hydrochloride hydrate be handled safely?
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SB-505124 hydrochloride hydrate is a Warning substance (GHS07) that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Store desiccated at 2-8°C.
How is SB-505124 hydrochloride hydrate packed and shipped?
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SB-505124 hydrochloride hydrate is supplied as a yellow powder and is typically stored desiccated at 2-8°C. We adhere to strict protocols for packaging and exporting chemicals globally.
How can I request a sample or quote for SB-505124 hydrochloride hydrate?
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To request a sample or a quotation for SB-505124 hydrochloride hydrate, please contact our sales team through the website or by phone. Provide the product name and CAS number for prompt service.
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