SB-525334
SB-525334 (CAS: 356559-20-1; C21H21N5; MW: 343.42 g/mol) is a yellow solid chemical supplied by Tech Serve Solutions. This compound functions as a potent tyrosine kinase inhibitor and has been utilised in research for studying TGFβ1-mediated human trophoblast differentiation. Its applications are primarily within cell biology and signal transduction research, particularly in areas related to kinase/phosphatase biology and neuroscience.
- IUPAC
- 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline

Research in Cell Biology
SB-525334 serves as a valuable tool in cell biology research. It has been employed to investigate specific cellular processes, such as TGFβ1-mediated human trophoblast differentiation.
Kinase and Phosphatase Signaling Studies
As a tyrosine kinase inhibitor, this compound is instrumental in studying kinase/phosphatase biology. Its activity aids in elucidating signaling pathways critical for cellular function and development.
Neuroscience and Cell Signaling Research
The compound is relevant for research in neuroscience and cell signaling. Its specific inhibitory action can be used to probe the roles of particular signaling cascades in these fields.
| Molecular weight | 343.42 |
|---|---|
| Empirical formula | C21H21N5 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: ≥20 mg/mL |
| Storage temperature | 2-8°C |
| Application | SB-525334 was used to study TGFβ1-mediated human trophoblast differentiation.7 |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB-525334 used for?
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SB-525334 is used in research, particularly for studying TGFβ1-mediated human trophoblast differentiation and in the fields of kinase/phosphatase biology, cell signaling, and neuroscience. It functions as a tyrosine kinase inhibitor.
What are the CAS number and formula for SB-525334?
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The CAS number for SB-525334 is 356559-20-1 and its molecular formula is C21H21N5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB-525334 with an assay of ≥98% (HPLC). This product is intended for research use and is not supplied as USP, BP, or EP grade.
How should SB-525334 be handled safely?
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SB-525334 is classified with GHS06 symbol and 'Danger' signal word. It has hazard statements H301, H315, H319, H335, and H413. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, faceshields, and gloves. Handle with appropriate caution to avoid dust inhalation and skin/eye contact.
How is SB-525334 packed, shipped, and exported?
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SB-525334 is supplied as a yellow solid and is stored at 2-8°C. As a specialist global supplier, Tech Serve Solutions exports chemicals worldwide in compliance with all relevant regulations.
How can I request a sample or quote for SB-525334?
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To request a sample or a quote for SB-525334, please contact our sales team through the website or by calling our direct line. We will be happy to assist you with your research needs.
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