SB-408124
SB-408124 (CAS: 288150-92-5), with the empirical formula C19H18F2N4O and a molecular weight of 356.37 g/mol, is a research chemical supplied by TSS. This off-white solid is primarily recognised for its role in investigating orexin A-mediated cardiovascular effects and blocking endogenous glucose production in preclinical studies. Its applications span cell biology, cell signalling, and neuroscience research.
- IUPAC
- N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N′-[4-(dimethylamino)phenyl]urea
Orexin A Research
SB-408124 has been utilised in studies to block orexin A-mediated cardiovascular effects in animal models, aiding research into the physiological roles of orexins.
Glucose Production Studies
This compound was employed to investigate the blockade of increased endogenous glucose production mediated by bicuculline in rats, contributing to metabolic research.
Bioactive Small Molecule Research
As a bioactive small molecule, SB-408124 serves as a valuable tool in cell biology and neuroscience research, particularly in areas related to cell signalling.
| Molecular weight | 356.37 |
|---|---|
| Empirical formula | C19H18F2N4O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |
| Application | SB-408124 was used to block orexin A-mediated cardiovascular effects in rats.1, It was used to study block the increase of endogenous glucose production mediated by bicuculline in rats.2 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB-408124 used for?
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SB-408124 is used in research to block orexin A-mediated cardiovascular effects and to study the blockade of endogenous glucose production. It is a tool in cell biology, cell signalling, and neuroscience.
What is the CAS number and formula for SB-408124?
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The CAS number for SB-408124 is 288150-92-5, and its empirical formula is C19H18F2N4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB-408124 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for SB-408124?
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SB-408124 is classified as a Warning with hazard statements H315, H319, and H335, indicating it may cause skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is SB-408124 packed and shipped?
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SB-408124 is typically stored at 2-8°C. TSS is a specialist global supplier and exporter of fine chemicals, ensuring proper packaging and adherence to shipping regulations for research chemicals.
How can I request a sample or quote for SB-408124?
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To request a sample or a quote for SB-408124, please contact the TSS sales team via our website or by calling our direct line.
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