SB-269970 hydrochloride
SB-269970 hydrochloride (CAS: 261901-57-9) is a selective 5-HT7 receptor antagonist with the molecular formula C18H28N2O3S · HCl and a molecular weight of 388.95 g/mol. This research chemical is primarily utilised in scientific studies to investigate the function of serotonin 5-HT7 receptors. It is particularly employed in neuropharmacological research to understand neurotransmission and signalling pathways.
- IUPAC
- (R)-3-[2-[2-(4-Methylpiperidin-1-yl)ethyl]pyrrolidine-1-sulfonyl]phenol hydrochloride,SB 269970A

Neuroscience Research
SB-269970 hydrochloride is used as a pharmacological tool to probe the role of 5-HT7 receptors in various neurological processes. Its selectivity allows researchers to investigate receptor-specific functions in vitro and in vivo.
Serotonin Receptor Studies
This compound serves as a valuable antagonist for studying the serotonin 5-HT7 receptor subtype. It has been employed to explore the involvement of these receptors in phenomena such as serotonin-induced hypothermia in rodent models.
Bioactive Small Molecule Research
As a bioactive small molecule, SB-269970 hydrochloride contributes to research in cell biology and signalling pathways. Its interaction with specific receptors provides insights into cellular communication mechanisms.
| Molecular weight | 388.95 |
|---|---|
| Empirical formula | C18H28N2O3S · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Solubility | H2O: soluble10 mg/mL, clear (warmed to 60 °C) |
| Storage temperature | 2-8°C |
| Application | SB-269970 was used to study the role of 5-HT7 receptors in serotonin-induced hypothermia in rodents.6 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR7(3363) |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB-269970 hydrochloride used for?
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SB-269970 hydrochloride is used as a selective 5-HT7 receptor antagonist in neuroscience and cell biology research to study the functions of serotonin receptors, including their role in neurotransmission and phenomena like serotonin-induced hypothermia.
What are the CAS number and formula for SB-269970 hydrochloride?
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The CAS number is 261901-57-9 and the empirical formula is C18H28N2O3S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB-269970 hydrochloride with an assay of ≥98% determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should SB-269970 hydrochloride be handled and stored?
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Handle SB-269970 hydrochloride with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store in a desiccated state at 2-8°C. The compound is classified under WGK Germany 3.
Is SB-269970 hydrochloride a controlled substance?
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The provided data does not indicate that SB-269970 hydrochloride is a controlled substance.
How is SB-269970 hydrochloride shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. SB-269970 hydrochloride is carefully packed and exported in compliance with international shipping regulations for research chemicals.
How can I request a quote or sample for SB-269970 hydrochloride?
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To request a quote or a sample of SB-269970 hydrochloride, please contact our sales department through the website or via direct inquiry.
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