SB-221284
SB-221284 (CAS: 196965-14-7), a compound with the molecular formula C16H14N3F3OS and a molecular weight of 353.36, is a research chemical supplied by TSS. It functions as an antagonist and has been utilised in studies investigating 5-HT2C receptor-mediated signalling in escape behaviour in rats. Available as a white solid, SB-221284 is primarily used in cell biology and neuroscience research settings.
- IUPAC
- 5-(Methylthio)-1-(3-pyridylcarbamoyl)-6-(trifluoromethyl)indoline
- Synonyms
- 5-(Methylthio)-1-(3-pyridylcarbamoyl)-6-(trifluoromethyl)indoline
Neuroscience Research
SB-221284 has been employed in preclinical research to investigate the role of the 5-HT2C receptor in behavioural studies, particularly in the context of escape behaviour in rodent models.
Cell Signaling Studies
As a selective antagonist, this compound is valuable for researchers studying the intricacies of cell signaling pathways involving serotonin receptors, contributing to a deeper understanding of neuronal communication.
Bioactive Small Molecule Research
This compound falls under the category of bioactive small molecules, making it a useful tool for drug discovery and development programmes exploring neurological targets.
| Molecular weight | 353.36 |
|---|---|
| Empirical formula | C16H14N3F3OS |
| Assay | >98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble ~14 mg/mL |
| Application | SB-221284 was administered to rats to study the effect of 5-HT2C receptor-mediated signaling in escape behavior.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB-221284 used for?
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SB-221284 is used as a research chemical, primarily in neuroscience and cell biology studies, to investigate 5-HT2C receptor-mediated signaling and its role in behaviour. It functions as an antagonist.
What is the CAS number and molecular formula for SB-221284?
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The CAS number for SB-221284 is 196965-14-7, and its molecular formula is C16H14N3F3OS.
What grade and purity does Tech Serve Solutions supply for SB-221284?
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Tech Serve Solutions supplies SB-221284 with a purity of >98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for SB-221284?
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Handling SB-221284 requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3.
How is SB-221284 packed, shipped, and exported?
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SB-221284 is typically supplied as a white solid. TSS is a specialist global supplier and exporter of fine chemicals and reagents, handling all necessary logistics and compliance for international shipment.
How can I request a quote or sample for SB-221284?
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To request a quote or sample for SB-221284, please contact our sales department through the TSS website or by phone.
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