SB-224289 hydrochloride

CAS 180084-26-8C32H32N4O3 · HClCell Biology

SB-224289 hydrochloride (CAS: 180084-26-8), with the molecular formula C32H32N4O3 · HCl and a molecular weight of 557.08 g/mol, is a bioactive small molecule. It is primarily utilized in neuroscience research as a selective antagonist for specific serotonin receptors, playing a role in understanding neurotransmission and cell signalling pathways. Supplied as an off-white solid, it is soluble in DMSO but insoluble in water.

IUPAC: 1′-Methyl-5-[[2′-methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4′-piperidine] hydrochloride,SB-224289A
Synonyms: 1′-Methyl-5-[[2′-methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4′-piperidine] hydrochloride,SB-224289A

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SB-224289 hydrochloride (C32H32N4O3 · HCl) — chemical structure, CAS 180084-26-8; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesCell BiologyNeuroscienceNeurotransmissionNeurotransmittersSerotonergics More...

01 /Applications

Neuroscience Research

SB-224289 hydrochloride serves as a valuable tool in neuroscience research for investigating the function of serotonin receptors, particularly the HTR1B subtype. Its antagonistic properties aid in elucidating the complex mechanisms of neurotransmission.

Cell Signaling Studies

This compound is employed in studies focused on cell signalling pathways, especially those modulated by serotonergic systems. It helps researchers understand how receptor activity influences cellular responses and functions.

Pharmacological Profiling

SB-224289 hydrochloride is used for the pharmacological profiling of serotonin receptors. Its selectivity allows for precise investigation into the roles of specific receptor subtypes in biological processes.

02 /Properties

Molecular weight	557.08
Empirical formula	C32H32N4O3 · HCl
Form	solid
Colour	off-white
Solubility	DMSO: soluble4.5 mg/mLH2O: insoluble

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

180084-26-8

MDL number

MFCD06407944

05 /Additional specifications

Gene Information	human ... HTR1B(3351)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SB-224289 hydrochloride used for?

SB-224289 hydrochloride is used in neuroscience research, particularly for studying serotonin receptors (e.g., human HTR1B), neurotransmission, and cell signalling pathways.

What is the CAS number and molecular formula for SB-224289 hydrochloride?

The CAS number is 180084-26-8, and the molecular formula is C32H32N4O3 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SB-224289 hydrochloride as a research-grade chemical. TSS does not represent this product as USP, BP, or EP grade.

What are the safety precautions when handling SB-224289 hydrochloride?

When handling SB-224289 hydrochloride, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. The substance has a WGK of 3 in Germany, indicating a high hazard.

How is SB-224289 hydrochloride shipped and exported?

SB-224289 hydrochloride is carefully packaged and exported by Tech Serve Solutions, adhering to all relevant shipping and customs regulations for chemical substances.