(S)-4-Chloro-α-methylbenzyl alcohol
(S)-4-Chloro-α-methylbenzyl alcohol (CAS 99528-42-4) is a chiral organic compound with the formula ClC6H4CH(CH3)OH and a molecular weight of 156.61 g/mol. It serves as a valuable building block in organic synthesis, particularly in asymmetric synthesis due to its chiral centre. This alcohol is frequently employed in the development of complex molecules and pharmaceutical intermediates.
- IUPAC
- (S)-4′-Chloro-1-phenylethanol,(S)-1-(4-Chlorophenyl)ethanol
- Synonyms
- (S)-1-(4-Chlorophenyl)ethanol(S)-4′-Chloro-1-phenylethanol
Chiral Building Block in Organic Synthesis
This enantiomerically pure alcohol is a key intermediate for the synthesis of more complex chiral molecules. Its defined stereochemistry is crucial for applications in asymmetric synthesis, leading to enantiopure target compounds.
Pharmaceutical Intermediate Development
The compound is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its structure allows for further functionalization, contributing to the creation of novel therapeutic agents.
Research and Development
In academic and industrial research, (S)-4-Chloro-α-methylbenzyl alcohol is used as a starting material or intermediate to explore new synthetic routes and molecular structures.
| Molecular weight | 156.61 |
|---|---|
| Linear formula | ClC6H4CH(CH3)OH |
| Assay | 95% |
| Density | 1.175 g/mL at 25 °C |
| Refractive index | n20/D 1.544 |
| Optical activity | [α]20/D -48.0°, c = 1 in chloroform |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-4-Chloro-α-methylbenzyl alcohol primarily used for?
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(S)-4-Chloro-α-methylbenzyl alcohol is primarily used as a chiral building block in organic synthesis and as an intermediate in the development of pharmaceuticals.
What are the CAS number and formula for (S)-4-Chloro-α-methylbenzyl alcohol?
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The CAS number is 99528-42-4 and the formula is ClC6H4CH(CH3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-4-Chloro-α-methylbenzyl alcohol with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should (S)-4-Chloro-α-methylbenzyl alcohol be handled safely?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and ensure adequate ventilation.
Is this chemical available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-4-Chloro-α-methylbenzyl alcohol.
How can I request a quote or sample?
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To request a quote or sample of (S)-4-Chloro-α-methylbenzyl alcohol, please contact our sales team through the website or via email.
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