(S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane
(S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane (CAS 16495-03-7) is a chiral building block with the molecular formula C13H18O3 and a molecular weight of 222.28 g/mol. This protected alcohol serves as a valuable intermediate in organic synthesis, particularly in asymmetric synthesis. Its defined stereochemistry and functional groups make it suitable for constructing complex chiral molecules in research and development settings.
- IUPAC
- 3-Benzyl-1,2-isopropylidene-sn-glycerol,D-α,β-Isopropylideneglycerol-γ-benzyl ether
- Synonyms
- 16495-03-7C13H18O33-Benzyl-1,2-isopropylidene-sn-glycerolD-α,β-Isopropylideneglycerol-γ-benzyl ether

Chiral Building Block
This compound is a key intermediate for introducing specific chirality into target molecules. It is frequently employed in multi-step syntheses where precise stereochemical control is essential.
Asymmetric Synthesis
Utilised in the construction of enantiomerically pure compounds. Its protected hydroxyl functionality allows for selective modifications at other positions within a synthetic route.
Organic Synthesis Intermediate
Serves as a versatile starting material or intermediate in the development of novel organic compounds. Its structure facilitates various chemical transformations.
| Molecular weight | 222.28 |
|---|---|
| Empirical formula | C13H18O3 |
| Assay | ≥95.0% (sum of enantiomers, GC) |
| Boiling point | 79-80 °C/0.05 mmHg(lit.) |
| Density | 1.050 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.496 |
| Optical activity | [α]20/D +21±1°, c = 4% in chloroform |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 100 °C / 212 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane used for?
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(S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane is primarily used as a chiral building block in asymmetric synthesis and as a general intermediate in organic synthesis for the construction of complex chiral molecules.
What is the CAS number and formula for (S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane?
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The CAS number is 16495-03-7 and the empirical formula is C13H18O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane with an assay of ≥95.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Please consult the Safety Data Sheet for full details. The flash point is 100 °C (212 °F).
How is this chemical packed, shipped, and exported?
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This chemical is packed according to industry standards for safe transport. Tech Serve Solutions is experienced in global shipping and export of fine chemicals.
How can I request a sample or quote?
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To request a sample or a quote, please use the contact form on our website or call our sales department directly.
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