(S)-4-Isopropylthiazolidine-2-thione
(S)-4-Isopropylthiazolidine-2-thione (CAS: 76186-04-4, C6H11NS2) is a chiral auxiliary utilised in asymmetric synthesis and chemical manufacturing. With a molecular weight of 161.29 g/mol, this compound is valued for its ability to be directly reduced to its corresponding aldehyde and the chiral auxiliary via reductive cleavage. Its high enantiomeric purity makes it an effective tool for stereoselective transformations in organic synthesis.
Chiral Auxiliary in Asymmetric Synthesis
This compound serves as a highly selective and efficient chiral auxiliary. It plays a crucial role in stereoselective organic transformations, enabling the synthesis of enantiomerically pure compounds.
Reductive Cleavage for Aldehyde Synthesis
It can be directly reduced using diisobutylaluminum hydride (DIBAL-H). This process yields both the corresponding aldehyde and regenerates the chiral auxiliary, facilitating efficient synthetic pathways.
Organic Synthesis Reagent
Utilised in various chemical synthesis processes, particularly where stereochemical control is paramount. Its specific structure aids in directing the stereochemical outcome of reactions.
| Molecular weight | 161.29 |
|---|---|
| Empirical formula | C6H11NS2 |
| Assay | ≥98.0% |
| Optical activity | [α]20/D -37±3°, c = 1 in chloroform |
| Optical purity | ee: ≥99:1 (LC) |
| Application | A highly selective and efficient chiral auxiliary1 which can be directly reduced to its corresponding aldehyde and the chiral auxiliary by reductive cleavage with diisobutylaluminum hydride.2 |
| Melting point | 69-71 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-4-Isopropylthiazolidine-2-thione used for?
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It is used as a highly selective and efficient chiral auxiliary in asymmetric synthesis and chemical synthesis. It facilitates direct reduction to its corresponding aldehyde and chiral auxiliary via reductive cleavage.
What is the CAS number and molecular formula for (S)-4-Isopropylthiazolidine-2-thione?
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The CAS number is 76186-04-4, and the molecular formula is C6H11NS2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-4-Isopropylthiazolidine-2-thione with an assay of ≥98.0% and optical purity of ee: ≥99:1 (LC). This is a technical/research grade; we do not represent it as USP, BP, or EP grade.
What are the safety considerations when handling (S)-4-Isopropylthiazolidine-2-thione?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany rating of 3.
How is (S)-4-Isopropylthiazolidine-2-thione packed, shipped, and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and adherence to international shipping regulations for chemical compounds like (S)-4-Isopropylthiazolidine-2-thione.
How can I request a sample or obtain a quote for (S)-4-Isopropylthiazolidine-2-thione?
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Samples and quotes can be requested directly through the Tech Serve Solutions website or by contacting our sales department.
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