(S)-4-Fluoro-α-methylbenzyl alcohol
(S)-4-Fluoro-α-methylbenzyl alcohol (CAS: 101219-73-2; Formula: FC6H4CH(CH3)OH; MW: 140.15) is a chiral fluorinated building block. This optically active alcohol is synthesised for its utility in asymmetric synthesis and as a key intermediate in the production of complex organic molecules. Its specific stereochemistry and the presence of a fluorine atom make it valuable in the development of pharmaceuticals and advanced materials.
- IUPAC
- (S)-1-(4′-Fluorophenyl)ethanol
- Synonyms
- (S)-1-(4′-Fluorophenyl)ethanol

Chiral Synthesis Intermediate
Utilised as a building block in the stereoselective synthesis of more complex chiral molecules. Its defined stereochemistry is crucial for creating enantiomerically pure compounds.
Pharmaceutical Research and Development
Serves as a precursor or intermediate in the synthesis of active pharmaceutical ingredients (APIs). The fluorine substituent can favourably modulate pharmacokinetic properties.
Material Science
Incorporated into the development of novel organic materials where specific stereochemical and electronic properties are required.
| Molecular weight | 140.15 |
|---|---|
| Linear formula | FC6H4CH(CH3)OH |
| Assay | 97% |
| Density | 1.111 g/mL at 25 °C |
| Refractive index | n20/D 1.502 |
| Optical activity | [α]20/D -49.0°, c = 1 in chloroform |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-4-Fluoro-α-methylbenzyl alcohol used for?
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(S)-4-Fluoro-α-methylbenzyl alcohol is primarily used as a chiral building block in organic synthesis, particularly in the pharmaceutical industry for developing new drug candidates and in material science.
What are the CAS number and chemical formula for (S)-4-Fluoro-α-methylbenzyl alcohol?
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The CAS number is 101219-73-2, and the chemical formula is FC6H4CH(CH3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-4-Fluoro-α-methylbenzyl alcohol with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and development or technical applications.
How should (S)-4-Fluoro-α-methylbenzyl alcohol be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., type ABEK respirator filter). Avoid inhalation of vapours and contact with skin and eyes. It is classified as harmful if swallowed and causes skin, eye, and respiratory irritation.
Is (S)-4-Fluoro-α-methylbenzyl alcohol a controlled substance?
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Based on the provided data, (S)-4-Fluoro-α-methylbenzyl alcohol is not listed as a controlled substance.
How is (S)-4-Fluoro-α-methylbenzyl alcohol packed and shipped?
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This chemical is shipped as a non-hazardous material, likely in appropriate containers for chemical transport, with the density being 1.111 g/mL at 25 °C. International export is available.
How can I request a quote or sample for (S)-4-Fluoro-α-methylbenzyl alcohol?
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Please contact our sales team via the website or phone to request a quotation or a product sample.
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