13-cis-Retinoic acid
13-cis-Retinoic acid (CAS: 4759-48-2), a retinoic acid isomer with the molecular formula C20H28O2 and a molecular weight of 300.44 g/mol, is a key compound in cell biology and cancer research. It functions as a bioactive small molecule, influencing gene regulation and cell signaling pathways. Primarily utilised in research settings, it serves as a valuable tool for understanding Vitamin A metabolism and its broader physiological effects.
- IUPAC
- Isotretinoin
Cancer Research
This compound is utilised in cancer research to investigate the role of retinoids in cell growth inhibition and differentiation. Its specific isomerisation can offer insights into targeted therapeutic strategies for various malignancies.
Cell Biology Studies
As a bioactive small molecule, 13-cis-Retinoic acid is employed in cell biology to explore cellular signalling pathways and gene expression regulation. It aids in understanding the complex mechanisms governing cell development and function.
Nutrition and Metabolism Research
Research into Vitamin A metabolism and its derivatives, including this retinoic acid isomer, is supported by this compound. It helps elucidate the biochemical processes involved in nutrient utilisation and physiological responses.
Pharmacological Investigations
The compound serves as a valuable reagent for pharmacological studies, particularly in exploring the effects of retinoids on nuclear receptors like PPAR and RXR. This aids in the development of new therapeutic agents.
| Molecular weight | 300.44 |
|---|---|
| Empirical formula | C20H28O2 |
| Assay | ≥98% (HPLC) |
| Storage temperature | −20°C |
| Melting point | 172-175 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-36/37/38 |
| Safety statements (S) | 53-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NOS2(4843), RARA(5914), RARB(5915) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 13-cis-Retinoic acid used for?
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13-cis-Retinoic acid is primarily used in cancer research, cell biology studies, nutrition research, and pharmacological investigations due to its role as a bioactive small molecule influencing gene regulation and cell signalling.
What are the CAS number and formula for 13-cis-Retinoic acid?
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The CAS number for 13-cis-Retinoic acid is 4759-48-2, and its molecular formula is C20H28O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 13-cis-Retinoic acid with an assay of ≥98% (HPLC). This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 13-cis-Retinoic acid be handled safely?
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13-cis-Retinoic acid is classified as Dangerous. Hazards include skin irritation (H315), serious eye irritation (H319), respiratory irritation (H335), and potential reproductive harm (H360). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filter).
Is 13-cis-Retinoic acid a controlled substance?
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The provided data does not indicate that 13-cis-Retinoic acid is a controlled substance.
How is 13-cis-Retinoic acid packed, shipped, and exported?
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13-cis-Retinoic acid is stored at -20°C. Specific packing, shipping, and export details are available upon request and comply with all relevant regulations for chemical export.
How can I request a sample or quote for 13-cis-Retinoic acid?
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To request a sample or quote for 13-cis-Retinoic acid, please contact our sales department through the website or via direct inquiry, providing your contact details and the quantity required.
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