(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane
(2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane (CAS 695816-47-8) is a chiral phospholane ligand supplied by Tech Serve Solutions. With a molecular weight of 264.30 g/mol, this compound is instrumental in asymmetric synthesis, particularly as a privileged ligand in catalytic processes. Its defined stereochemistry allows for precise control in forming enantiomerically pure products, making it a valuable reagent for complex chemical transformations.
- IUPAC
- S,S-Me-RajPhos™
- Synonyms
- 5-dimethylphospholane695816-47-8C15H21O2P
Asymmetric Catalysis
This phospholane ligand is extensively used in asymmetric catalysis to achieve high enantioselectivity in various chemical reactions. Its unique structure enables it to coordinate effectively with transition metals, forming active catalytic species for chiral synthesis.
Privileged Ligand in Synthesis
As a member of the DuPhos and BPE ligand family, (2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane is recognized as a privileged ligand. It facilitates challenging transformations, including asymmetric hydrogenations and cross-coupling reactions.
Chiral Intermediate Synthesis
The compound serves as a key component in the synthesis of enantiomerically pure intermediates for pharmaceuticals and fine chemicals. Its application ensures stereochemical integrity throughout multi-step synthetic routes.
| Molecular weight | 264.30 |
|---|---|
| Empirical formula | C15H21O2P |
| Density | 1.103 g/mL at 25 °C |
| Refractive index | n20/D 1.5713 |
| Optical activity | [α]/D +35°, c = 1 in chloroform |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,5S)-(+)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane used for?
+
This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, enabling the selective formation of enantiomerically pure products.
What is the CAS number and molecular formula?
+
The CAS number is 695816-47-8, and the molecular formula is C15H21O2P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical for research and synthesis purposes. The specific grade and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, EP, or BP grade.
How should this chemical be handled and stored?
+
This compound is combustible with a flash point above 110 °C (230 °F). Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet for detailed handling and storage recommendations.
Is this chemical suitable for use in pharmaceutical manufacturing?
+
While used in chiral synthesis for pharmaceutical intermediates, the supplied grade is intended for research and development. For large-scale manufacturing, specific quality agreements and purity assessments are required.
How is this product shipped and exported?
+
Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations for hazardous and non-hazardous materials. Please contact us for specific export inquiries.
How can I request a sample or a quote?
+
To request a sample or a quotation, please use the 'Request a Quote' or 'Sample Request' form on our website, or contact our sales team directly with your requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis