(2S,5S)-(–)-5-Benzyl-3-methyl-2-(5-methyl-2-furyl)-4-imidazolidinone
(2S,5S)-(–)-5-Benzyl-3-methyl-2-(5-methyl-2-furyl)-4-imidazolidinone (CAS 415678-40-9) is a chiral organocatalyst with a molecular weight of 270.33. This compound, possessing the empirical formula C16H18N2O2, is a valuable reagent in asymmetric synthesis. Its primary application lies in facilitating highly selective Diels-Alder reactions, particularly with simple α,β-unsaturated ketones, making it a key component in sophisticated chemical synthesis.
- IUPAC
- (2S,5S)-3-Methyl-2-(5-methyl-2-furanyl)-5-(phenylmethyl)-4-imidazolidinone
- Synonyms
- (2S,5S)-3-Methyl-2-(5-methyl-2-furanyl)-5-(phenylmethyl)-4-imidazolidinone
Asymmetric Diels-Alder Reactions
This imidazolidinone organocatalyst is highly effective in promoting asymmetric Diels-Alder reactions. It demonstrates significant selectivity when reacting with simple α,β-unsaturated ketones, enabling the stereocontrolled synthesis of complex cyclic structures.
Chiral Synthesis
As a chiral reagent, it plays a crucial role in asymmetric synthesis pathways. Its specific stereochemistry allows for the introduction of chirality into target molecules, which is essential in the development of pharmaceuticals and fine chemicals.
MacMillan Imidazolidinone Catalysis
This compound is a key member of the MacMillan imidazolidinone class of organocatalysts. These catalysts are widely recognised for their efficiency and selectivity in various stereoselective transformations.
| Molecular weight | 270.33 |
|---|---|
| Empirical formula | C16H18N2O2 |
| Assay | 95% |
| Refractive index | n20/D 1.5598 |
| Application | Highly selective organocatalyst for the Diels-Alder reaction with simple α,β−unsaturated ketones.4 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,5S)-(–)-5-Benzyl-3-methyl-2-(5-methyl-2-furyl)-4-imidazolidinone used for?
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(2S,5S)-(–)-5-Benzyl-3-methyl-2-(5-methyl-2-furyl)-4-imidazolidinone is primarily used as a highly selective organocatalyst for asymmetric Diels-Alder reactions with simple α,β-unsaturated ketones.
What is the CAS number and formula for this compound?
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The CAS number is 415678-40-9, and the empirical formula is C16H18N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of 95%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should this chemical be handled safely?
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This compound is classified as toxic if swallowed and causes skin and serious eye irritation. It may also cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling information.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that this chemical is a controlled substance.
How is this chemical packed and shipped?
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This chemical is packed and shipped according to international regulations for hazardous materials, including UN 2810, 6.1, PGIII classification. TSS ensures compliant global export.
How can I request a sample or quote?
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To request a sample or obtain a quote, please contact our sales department through the website or provide your details via the online inquiry form.
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