(2S,5S)-(–)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-diethylphospholane
(2S,5S)-(–)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-diethylphospholane (CAS: 1314246-02-0) is a chiral phospholane ligand of interest in asymmetric synthesis. With a molecular weight of 292.35 g/mol, this compound is utilised in catalytic processes, particularly where stereoselectivity is critical. It belongs to the family of DuPhos and BPE ligands, known for their high efficiency and application in advanced chemical synthesis and the preparation of complex molecules.
- IUPAC
- S,S-Et-RajPhos™
- Synonyms
- 5-diethylphospholaneS,S-Et-RajPhos™

Asymmetric Catalysis
This phospholane ligand is employed in asymmetric catalytic reactions, enabling the stereoselective synthesis of chiral molecules. Its structure facilitates high enantioselectivity in various transformations.
Chiral Ligand
As a privileged chiral ligand, it is valuable in metal-catalysed reactions requiring precise control over stereochemistry. It is particularly relevant in organometallic chemistry and homogeneous catalysis.
Chemical Synthesis
Used as a building block or catalyst component in complex organic synthesis, it aids in constructing molecules with defined stereocentres. Its applications span research and development in fine chemicals and pharmaceuticals.
| Molecular weight | 292.35 |
|---|---|
| Empirical formula | C17H25O2P |
| Density | 1.0760 g/mL at 25 °C |
| Refractive index | n20/D 1.5581 |
| Optical activity | [α]22/D -36°, c = 1 in chloroform |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,5S)-(–)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-diethylphospholane used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly in metal-mediated reactions that require high stereoselectivity.
What is the CAS number and formula for this chemical?
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The CAS number is 1314246-02-0, and its empirical formula (Hill notation) is C17H25O2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a typical purity of >98%. It is supplied as a research or technical grade material and is not intended for USP, BP, EP, or other pharmacopoeial applications unless explicitly stated.
How should this chemical be handled safely?
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This compound has a flash point of >110 °C (>230 °F) and is classified under WGK 2 in Germany. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding ignition sources.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs and ships this chemical according to international regulations for hazardous materials. As a global supplier, we manage export logistics for research and industrial clients worldwide.
How can I request a sample or quote for this product?
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To request a sample or a quote, please use the contact form on our website or email our sales department, providing the product name and CAS number (1314246-02-0).
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