(2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine
(2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine (CAS 219794-79-3) is a chiral organic compound with the molecular formula C10H19NO and a molecular weight of 169.26 g/mol. This quinuclidine derivative is recognised for its utility in asymmetric synthesis and as a chiral building block in complex molecule construction. It serves as a valuable reagent in specialised chemical synthesis, particularly where precise stereochemical control is paramount, finding application in catalysis and ligand development.
- IUPAC
- (2S,4S,5R)-5-Ethyl-2-quinuclidinylmethanol
- Synonyms
- 219794-79-3(2S,4S,5R)-5-Ethyl-2-quinuclidinylmethanol
Asymmetric Synthesis
This compound serves as a chiral auxiliary or ligand in asymmetric synthesis, facilitating the stereoselective formation of enantiomerically enriched products. Its defined stereochemistry is crucial for controlling reaction outcomes in the creation of complex chiral molecules.
Chiral Catalyst and Ligand Development
As a derivative of privileged structures, (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine is employed in the development of novel chiral catalysts and ligands for various transition metal-catalyzed reactions. It enables the fine-tuning of catalyst performance and selectivity.
Pharmaceutical Intermediates
Its chiral nature makes it a potential building block in the synthesis of pharmaceutically active compounds. The quinuclidine core is found in several known drugs, and derivatives like this can be used in the development of new therapeutic agents.
Research and Development
Used in academic and industrial research settings for exploring new synthetic methodologies and developing novel chemical entities. It provides a stereochemically defined scaffold for advanced organic chemistry investigations.
| Molecular weight | 169.26 |
|---|---|
| Empirical formula | C10H19NO |
| Assay | ≥98.0% |
| Refractive index | n20/D 1.500 |
| Optical activity | [α]/D +17±1°, c = 1% in chloroform |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine used for?
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(2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine is primarily used in asymmetric synthesis, as a chiral catalyst or ligand component, and in the development of pharmaceutical intermediates and novel chemical entities in research settings.
What is the CAS number and molecular formula for this compound?
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The CAS number is 219794-79-3, and the molecular formula is C10H19NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine with an assay of ≥98.0%. This is a research-grade chemical and not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation, avoid breathing dust/fume/gas/mist/vapours/spray, and avoid contact with eyes and skin. Refer to the Safety Data Sheet for full details.
Is this compound a controlled substance?
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The provided data does not indicate that (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping and handling regulations. Specific packaging details for (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine will be provided upon request and in accordance with destination country requirements.
How can I request a sample or quote?
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To request a sample or quote for (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine, please contact our sales team through the website or via the provided contact details, specifying your requirements.
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